English
What Are You Looking For?
23-Hydroxybetulinic Acid Standard (≥98% HPLC) | CAS 85999-40-2
23-Hydroxybetulinic Acid (CAS: 85999-40-2) is a bioactive triterpenoid isolated from natural sources like Pulsatilla chinensis, renowned for its potent antitumor properties. With molecular formula C₃₀H₄₈O₄ and high purity (≥98% HPLC-verified), this compound serves as a critical reference standard in oncology and pharmacology research.
Product Name :
23-Hydroxybetulinic AcidCAS No. :
85999-40-2Appearance :
Fine White PowderSpecification :
98%CAS No.: 85999-40-2
Molecular Formula: C₃₀H₄₈O₄
Molecular Weight: 472.70
Next-Gen Anticancer & Antidiabetic Triterpenoid
≥98% Pure: Off-white crystalline powder (Pharma Grade)
Mechanism-Validated Benefits:
Metastasis Suppressor: Inhibits MMP-9/FAK/Src pathways.
Antidiabetic Activity: Enhances insulin sensitivity.
Antiviral Potency: 3.7x stronger HIV-1 protease inhibition vs. betulinic acid.
Neuroprotection: Reduces Aβ plaque formation in Alzheimer’s models.
| Parameter | Detail |
|---|---|
| Purity | ≥98% (HPLC-ELSD) |
| Identification | ¹H/¹³C-NMR, Mass |
| Solubility | Soluble in DMSO, methanol; sparingly soluble in water (0.02 g/L at 25°C) |
| Melting Point | 226-228°C |
| Specific Rotation | +15° (c=0.1, pyridine) |
| Storage | 2-8°C (vacuum-sealed, amber vials; <0.1% O₂) |
| Shelf Life | 24 months |
| Industry | Use Cases |
|---|---|
| Pharmaceuticals | - Antimetastatic drug leads (Phase II preclinical) - Type 2 diabetes therapeutics |
| Cosmeceuticals | - Anti-glycation creams (prevents AGE formation) - Melanogenesis inhibitor for brightening serums |
| Nutraceuticals | - Glucose metabolism support blends - Nootropic stacks for cognitive decline |
| Veterinary | - Equine metabolic syndrome management - Canine cognitive dysfunction supplements |
Enhanced Bioactivity: 2.1x greater apoptosis induction in drug-resistant cancers vs. betulinic acid.
Dual Targeting: Simultaneously modulates insulin signaling + cancer metastasis pathways.
Patent-Pending Delivery: Lyophilized nanoparticles.
Eco-Extraction: Closed-loop bioreactor synthesis from Betula platyphylla.
Bulk: 250 g/vacuum aluminum canisters (nitrogen flushed)
Samples: 25 mg, 100 mg in argon-filled HPLC vials
Stability: 98.2% purity retention after 18 months (2-8°C, desiccated)
Cyclopamine 98% (CAS: 4449-51-8), a potent steroidal alkaloid targeting the Hedgehog pathway, selectively inhibits Smoothened (Smo) with IC50 of 46 nM. This pharma-grade inhibitor is validated for oncology research (pancreatic/basal cell carcinoma) and stem cell differentiation studies.
Read More
Ingenol is a high-purity pharmaceutical intermediate derived from natural plant sources. Our product guarantees over 99.0% purity and rigorous quality control, ensuring reliability for research and production needs . With competitive pricing and flexible global logistics, we provide seamless supply chain support to meet diverse customer demands.
Read More
A naturally derived pentacyclic triterpenoid, Lupeol is extracted from plant sources such as strawberries, mangoes, and traditional herbs. With over 99% HPLC purity, our Lupeol meets rigorous pharmaceutical standards for research and production.
Read More
Curculigoside is a high-purity phenolic glycoside isolated from Curculigo species, extensively utilized in pharmacological research for its potent bioactivities. With HPLC-confirmed purity ≥98%, this compound serves as a critical reference standard in drug discovery and mechanistic studies.
Read More
Phorbol 12-Myristate 13-Acetate (PMA) 98% (CAS:16561-29-8) is an ultra-pure, crystalline PKC activator derived from Croton tiglium seeds, validated for tumor promotion and immunology research. With ≥98% HPLC-verified purity, it reliably induces PKC-dependent pathways at 1-100 nM concentrations in models ranging from DMBA-initiated carcinogenesis to neutrophil NETosis studies.
Read More
IPv6 network supported