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Acacetin (CAS 480-44-4) HPLC ≥98% pure yellow crystalline flavonoid. Clinically validated for anticancer (breast/liver), neuroprotective (Alzheimer’s models), and anti-inflammatory effects.
Soluble in DMSO/ethanol. GMP-grade, bulk OEM. COA included.
Product Name :
AcacetinCAS No. :
480-44-4Appearance :
Yellow crystalline powderSpecification :
98%CAS No.: 480-44-4
Molecular Formula: C₁₆H₁₂O₅
Molecular Weight: 284.26
Potent Anticancer, Antioxidant & Neuroprotective Flavonoid
≥98% Pure: Yellow crystalline powder (Pharma/Cosmetic Grade)
Clinically Validated Benefits:
Anticancer Activity: Induces apoptosis in breast/liver cancer cells.
Antioxidant Effects: Neutralizes ROS, enhances cellular glutathione levels, protects mitochondrial function.
Neuroprotective: Crosses BBB, inhibits neuroinflammation.
| Parameter | Detail |
|---|---|
| Purity Range | ≥98% (HPLC/UV) |
| Identification | HPLC, NMR, FT-IR, Mass Spectrometry |
| Solubility | Soluble in DMSO, ethanol; insoluble in water (<0.1 g/L at 25°C) |
| Melting Point | 262-264°C |
| Storage | 2-8°C (desiccated, amber glass; argon atmosphere) |
| Shelf Life | 24 months |
| Industry | Use Cases |
|---|---|
| Pharmaceuticals | - Targeted cancer therapies - Neurodegenerative disease drug candidates |
| Nutraceuticals | - Cognitive health supplements - Antioxidant blends for metabolic syndrome |
| Cosmeceuticals | - UV-protective serums - Anti-redness formulations |
| Functional Foods | - Neuroprotective functional beverages - Stability-enhanced health bars |
Bioavailability Enhanced: Nanoemulsion/liposome delivery options available.
Multi-Target Efficacy: Simultaneously modulates cancer pathways + neuroinflammation.
Eco-Sourcing: Ethically wildcrafted from Robinia pseudoacacia.
Regulatory Compliance: USP/EP heavy metals <2 ppm; residual solvents ≤0.1%.
Bulk: 500 g/vacuum-sealed aluminum canister (oxygen absorber included).
Samples: 10 mg, 50 mg, 100 mg in argon-filled amber vials.
Storage: Stable for 24 months at 2-8°C under inert gas; thaw-freeze cycles ≤3.
Cutting-Edge Isolation:
preparative HPLC (purity >99.0% achievable).
Peer-Validated Mechanisms:
studies confirming anticancer/neuroprotective effects.
Supply Chain Flexibility:
Custom concentrations98%, scale from grams to 100 kg.
End-to-End Documentation:
Batch-specific COA, LC-MS spectra, stability data, and cytotoxicity reports.
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