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Schisandrol A 98% Supplier: CAS 7432-28-2, HPLC Verification & Bulk Buying Guide Quick Answer Schisandrol A (also known as Schisandrin or Schizandrin, CAS 7432-28-2) is the principal dibenzocyclooctadiene lignan of Schisandra chinensis fruit. When sourcing Schisandrol A 98%, the single most important verification point is whether the supplier's HPLC method actually separates Schisandrol A from its closely related isomers (Schisandrol B, Schisandrin B and C, gomisin-type lignans) — a generic purity number alone cannot tell you this. Request the batch chromatogram, confirm the main peak identity, and check storage and packaging details before scaling to commercial quantities. Key Takeaways · Schisandrol A = Schisandrin (Schizandrin): one compound, several names — confirm which one your specification means before comparing quotations. · Schisandra lignans form a family of structurally similar isomers; HPLC methods must resolve them, and "98%" without a chromatogram proves nothing. · ≥98% HPLC is the common high-purity grade for ingredient development and research use. · The compound is sensitive to light and moisture over time; cool, dry, light-protected storage protects batch consistency. · For US-bound supply, confirm the intended use and regulatory pathway with your own regulatory team — documentation requirements depend on the application. 1. Chemical Identity and Specifications Item Specification Product Name Schisandrol A (Schisandrin; Schizandrin) CAS Number 7432-28-2 Molecular Formula C₂₄H₃₂O₇ Molecular Weight 448.51 g/mol Compound Class Dibenzocyclooctadiene lignan Botanical Source Fruit of Schisandra chinensis (Chinese magnolia vine) Appearance White to off-white crystalline powder Purity ≥98% (HPLC) Solubility Soluble in methanol, ethanol, DMSO; low solubility in water Documentation COA, HPLC, MS/NMR, SDS, TDS per batch Naming note: suppliers and literature use Schisandrol A, Schisandrin and Schizandrin interchangeably for CAS 7432-28-2. Some catalogs list "Schisandrol B" as a separate compound (a different, more saturated lignan). Because the names look similar, always match quotations by CAS number, not by name alone. 2. Schisandrol A 98% vs. Standardized Schisandra Extract Parameter Schisandrol A 98% (purified) Schisandra extract (standardized) Composition Single lignan compound Complex extract with multiple Schisandra lignans Purity basis ≥98% Schisandrol A by HPLC Total lignans or Schisandrol A content standardized Typical use Ingredient development, analytical reference, research Formulations where a defined extract is acceptable Analytical identity Single dominant peak with resolved isomer region Multi-peak lignan fingerprint Price logic Purity- and process-driven Raw-material- and ratio-driven Both product types are legitimate — the procurement risk is buying one while believing you ordered the other. Put the CAS number and the purity basis in your specification sheet before requesting quotations. 3. HPLC Verification: The Isomer Question This is where Schisandrol A sourcing differs from most botanical single compounds. Schisandra chinensis contains a family of closely related dibenzocyclooctadiene lignans — Schisandrol A, Schisandrol B, Schisandrin B, Schisandrin C, gomisin A, gomisin N and others — several of which elute close together on typical reversed-phase methods. When auditing a Schisandrol A 98% batch file: 1. Ask for the full chromatogram, not the purity figure. Check that the isomer region is resolved and that minor lignan peaks are reported. 1. Confirm main-peak identity. MS or NMR data should support that the dominant peak is Schisandrol A (CAS 7432-28-2), not a co-eluting isomer such as Schisandrol B. 1. Method transparency. Column type, mobile phase, wavelength and integration parameters should be stated, so your own lab can reproduce the result. 1. Impurity and residue data. Residual solvents and heavy metals should match the requirements applicable to your market and intended use. 1. Batch traceability. The COA batch number must match the drum labels of the shipment you receive. A practical sequence used by many procurement teams: order a 20 g sample with full documentation, run independent HPLC (ideally with an isomer-resolution check) at a third-party laboratory, then scale. CQ HERB supports this sample-first model with batch-specific documentation. 4. Stability, Packaging and Storage · Light and moisture: lignans gradually degrade under light exposure and humid conditions; containers should be sealed and light-protected. · Storage: cool and dry, protected from light; follow the SDS/TDS for the specific grade. Research-grade solutions in DMSO are typically stored frozen in aliquots. · Shelf life: typically 24 months under recommended conditions; check the retest date on the COA. · Formulation note: low water solubility — ethanol, glycol or DMSO-based premixes are common in development work. Confirm compatibility with your system early. · Shipping: standard sealed export packaging; for humid climates, confirm desiccant and moisture-barrier arrangements with your supplier. 5. Intended Applications and Regulatory Context Schisandrol A 98% is supplied for: · Ingredient development and research — as a reference compound and botanical-derived active for phytochemistry, analytical method development and natural-product research. · Formulation development — as a raw material for product development teams working with Schisandra-derived ingredients. Regulatory note: Schisandra chinensis extracts are familiar to North American and European buyers, but permitted use, labeling and claim language differ by market and application. Confirm the intended use and applicable framework with your regulatory team. CQ HERB supplies the ingredient with technical documentation — it is not a finished product and carries no product claims. 6. Supplier Evaluation Checklist · Full HPLC chromatogram with resolved isomer region · Main-peak identity confirmed by MS or NMR · Quotation matched by CAS number, not by product name · Heavy metals and residual solvents reported · Botanical source and extraction process described transparently · COA / SDS / TDS internally consistent · Sample available for third-party verification · Moisture-barrier packaging and light-protected storage confirmed · Multi-batch supply stability and lead-time transparency Nanjing Spring & Autumn Biological Engineering Co., Ltd. (CQ HERB) supplies Schisandrol A 98% with batch-based documentation including COA, HPLC analytical data, MS/NMR, SDS and TDS, and supports sample evaluation before bulk orders. Our quality management system is certified to ISO 9001. 7. Bulk Ordering Practicalities · Sample stage: 20 g with full documentation for independent verification. · Development quantities: 100 g–1 kg for pilot work. · Commercial quantities: multi-kg volumes scheduled against forecast; quoted on request. · Packaging: double PE bags in fiber drums; foil pouches for small batches; moisture-barrier protection for humid destinations. · Lead time: confirm current stock and production schedule at quotation. FAQ Q: What is the CAS number of Schisandrol A? A: CAS 7432-28-2. Schisandrol A is also known as Schisandrin or Schizandrin; molecular formula C₂₄H₃₂O₇, MW 448.51 g/mol. Q: Are Schisandrol A and Schisandrol B the same compound? A: No. They are distinct lignans found in the same plant. Match your specification by CAS number and confirm the HPLC method resolves the isomers. Q: What purity grade should I buy? A: ≥98% HPLC is the common high-purity grade for ingredient development and research use; standardized Schisandra extracts are a separate product category. Q: Why is the chromatogram more important than the purity number? A: Because Schisandra lignans are structurally similar, a method that does not resolve the isomer region can overstate the purity of a specific compound. The chromatogram shows what the number hides. Q: How should Schisandrol A be stored? A: Cool, dry, light-protected, in tightly sealed containers. Refer to the SDS/TDS for batch-specific guidance. Q: Can I get a sample before a bulk order? A: Yes. CQ HERB provides sample quantities with batch-specific documentation so buyers can complete independent verification first. Conclusion Schisandrol A sourcing rewards suppliers who can prove isomer-level analytical control. Match quotations by CAS number, audit the full chromatogram rather than a single purity figure, plan for low water solubility and light-protected storage, and validate the regulatory pathway for your market. A supplier with transparent batch documentation and sample-first evaluation removes most of the risk before the first drum ships. Related reading: Schisandra chinensis Extracts — Product Category · Natural Active Compounds · Ruscogenin 98% Supplier: CAS 472-11-7 Sourcing Guide Contact CQ HERB for Schisandrol A 98% specifications, samples, and bulk supply inquiries — Ives Shen, International Sales Dept. · sale05@cqherb.com · www.cqherb.com

Ruscogenin 98% Supplier: CAS 472-11-7, HPLC Purity & Bulk Sourcing Guide Quick Answer Ruscogenin (CAS 472-11-7) is a steroidal sapogenin obtained primarily from Ruscus aculeatus (butcher's broom) root. When sourcing Ruscogenin 98%, verify four things before ordering: a batch-specific HPLC chromatogram, the botanical source statement, identity confirmation data (MS/NMR or IR), and storage-relevant documentation. Because the material is a purified single compound with a defined melting range, identity and purity can be checked analytically — which is why buyers should insist on real batch data rather than a template COA. Key Takeaways · Ruscogenin is a steroidal sapogenin (C₂₇H₄₂O₄, MW 430.63), not a standardized plant extract — the two are different products with different price logic. · ≥98% HPLC is the common high-purity specification used in ingredient development and research applications. · Request batch COA + actual HPLC chromatogram + MS/NMR data; confirm the batch number on the documents matches your shipment. · Storage at 2–8 °C, light-protected, matters: ruscogenin is sensitive to prolonged air and light exposure. · Solubility in water is low; formulations typically rely on ethanol- or glycol-based systems — confirm the grade and presentation with your supplier early. · Documentation expectations differ by market; for US-bound cosmetic or research supply, confirm the intended use with your regulatory team. 1. Chemical Identity and Specifications Item Specification Product Name Ruscogenin (Ruscogenine) CAS Number 472-11-7 Molecular Formula C₂₇H₄₂O₄ Molecular Weight 430.63 g/mol Botanical Source Ruscus aculeatus L. root (butcher's broom) Appearance White to off-white crystalline powder Purity ≥98% (HPLC) Melting Point 182–186 °C Solubility Soluble in DMSO, ethanol; low solubility in water Storage 2–8 °C, protected from light and moisture Documentation COA, HPLC, MS/NMR, SDS, TDS per batch Ruscogenin belongs to the spirostane-type steroidal sapogenins. Its defined melting range and single-compound nature make it practical to verify identity by melting point determination, IR, or MS, in addition to HPLC purity — a useful cross-check when evaluating a new supplier. 2. Ruscogenin 98% vs. Standardized Butcher's Broom Extract Buyers frequently compare quotations for products that are not equivalent: Parameter Ruscogenin 98% (purified) Butcher's broom extract (standardized) Composition Single steroidal sapogenin Complex extract containing ruscogenin plus other saponins Purity basis ≥98% Ruscogenin by HPLC Ruscogenin content standardized to a stated level Typical use Ingredient development, analytical reference, research Formulations where a defined extract is acceptable Price logic Purity- and process-driven Raw-material- and ratio-driven Analytical identity Sharp single HPLC peak Multi-peak botanical fingerprint If your specification calls for "98% ruscogenin", a 10%–30% standardized extract will not satisfy it, regardless of the price difference. Confirm the analytical basis in writing before comparing costs. 3. HPLC and COA Verification: What to Check A credible Ruscogenin 98% batch file should include: 1. Batch-specific HPLC chromatogram — with column type, mobile phase, detection wavelength, and integration parameters, not just a percentage. 1. Identity confirmation — MS and/or NMR data supporting the spirostane structure; melting point within 182–186 °C is a quick secondary check. 1. Impurity profile — related sapogenins and process-related impurities, reported or stated as within specification. 1. Residual solvents and heavy metals — results should match the requirement set applicable to your market and intended use. 1. SDS and TDS — consistent with the COA and current for the grade supplied. 1. Batch traceability — the batch number on the COA must match the labels on the drums you receive. A practical procurement sequence: request a 20 g sample with the full documentation package, run independent HPLC verification at a third-party laboratory, then scale to commercial quantities. CQ HERB supports this sample-first evaluation model with batch-specific documentation. 4. Solubility, Formulation Handling and Stability Ruscogenin is poorly water-soluble, which shapes how formulators work with it: · Solvent systems: ethanol, glycol, or DMSO-based premixes are common in development work; confirm compatibility with your final system early. · Thermal exposure: keep processing temperatures well below the melting range and avoid prolonged heat during incorporation. · Light and air: the material should be handled in closed containers, protected from light; long exposure to air reduces content over time. · Storage: 2–8 °C, dry, light-protected. Shelf life is typically stated as 36 months under recommended conditions; check the retest date on the COA. · Shipping: for warm-climate destinations, confirm insulated packaging and transit documentation with your supplier — heat exposure during transit is a common, avoidable quality issue. 5. Intended Applications and Regulatory Context Ruscogenin 98% is supplied for: · Cosmetic raw-material development — used by formulators as a botanical-derived active ingredient in skin and body care development; finished-product claims are the responsibility of the brand and must comply with the applicable cosmetic regulation in the destination market. · Research and analytical applications — as a reference compound for phytochemical, chromatographic, and natural-product research. Regulatory note: permitted use, labeling, and claim language for ruscogenin-containing products differ by market. US-bound supply may fall under cosmetic ingredient or research-material frameworks depending on intended use and how the material is presented; buyers should confirm the applicable pathway with their regulatory team. CQ HERB supplies the ingredient with technical documentation — it is not a finished product and carries no product claims. 6. Supplier Evaluation Checklist · Batch-specific HPLC chromatogram provided · MS/NMR or IR identity data available · Melting range stated and consistent with specification · Heavy metals and residual solvents reported · Botanical source and extraction process described transparently · COA / SDS / TDS internally consistent · Sample available for third-party verification · Cold-chain or insulated shipping arranged for warm destinations · Multi-batch supply stability and lead-time transparency Nanjing Spring & Autumn Biological Engineering Co., Ltd. (CQ HERB) supplies Ruscogenin 98% with batch-based documentation including COA, HPLC analytical data, MS/NMR, SDS and TDS, and supports sample evaluation before bulk orders. Our quality management system is certified to ISO 9001. 7. Bulk Ordering Practicalities · Sample stage: 5 g with full documentation, suitable for independent verification. · Development quantities: 25 g–100 g for pilot formulation work. · Commercial quantities: 500 g–1 kg and above, scheduled against forecast; larger volumes quoted on request. · Packaging: sealed, moisture-barrier inner packaging in outer drums; cold-chain or insulated options for warm-climate destinations. · Lead time: confirm current stock and production schedule at quotation. FAQ Q: What is the CAS number of Ruscogenin? A: CAS 472-11-7; molecular formula C₂₇H₄₂O₄; molecular weight 430.63 g/mol. Q: Is Ruscogenin the same as butcher's broom extract? A: No. Ruscogenin is a single purified steroidal sapogenin; butcher's broom extract is a complex botanical preparation that may be standardized to a stated ruscogenin content. Q: What purity should I specify? A: ≥98% HPLC is the common high-purity grade for ingredient development and research use. Standardized extracts are a separate product category. Q: How should Ruscogenin 98% be stored? A: 2–8 °C, dry, protected from light, in tightly closed containers. Refer to the SDS/TDS for the specific grade. Q: Can I receive a sample before a bulk order? A: Yes. CQ HERB provides 20 g samples with batch-specific documentation so buyers can complete independent verification first. Q: Does Ruscogenin dissolve in water? A: Solubility in water is low. Ethanol, glycol, or DMSO-based systems are typically used in development work; discuss your formulation format with the supplier. Conclusion Sourcing Ruscogenin 98% comes down to verification discipline: confirm you are comparing a purified compound against a standardized extract, audit the batch-specific HPLC and identity data, plan for low water solubility and cool, light-protected storage, and validate the regulatory pathway for your market and intended use. A supplier that provides real batch documentation and sample-first evaluation removes most of the risk from the purchase. Related reading: Ruscogenin (CAS 472-11-7): A High-Purity Steroidal Sapogenin for Advanced Research · Natural Active Compounds · Cosmetic Active Ingredients Contact CQ HERB for Ruscogenin 98% specifications, samples, and bulk supply inquiries — Ives Shen, International Sales Dept. · sale05@cqherb.com · www.cqherb.com

Glabridin (CAS 59870-68-7) is a prenylated isoflavan purified from the root of Glycyrrhiza glabra (licorice). When sourcing Glabridin 98%, buyers should verify three things before placing an order: batch-specific HPLC chromatograms (not just a COA summary), botanical origin and extraction process documentation, and heavy-metal and residual-solvent data consistent with the destination market's cosmetic or research-use regulations. Reputable suppliers provide 20 g-scale samples with complete documentation before commercial quantities. Key Takeaways · Glabridin is the key purified isoflavan in licorice root; commercial grades range from standardized licorice extracts (10%–40%) to high-purity ≥98% HPLC material. · "98% Glabridin" and "licorice extract standardized to 40% glabridin" are different products with different price structures — confirm which one you are comparing. · Always request: batch COA, HPLC chromatogram, SDS, heavy metals, residual solvents, and botanical source statement. · Glabridin is light- and oxidation-sensitive; packaging and storage conditions directly affect batch-to-batch consistency. · Regulatory status differs by market and application — confirm the intended use (cosmetic ingredient, research compound) with your regulatory team before purchase. 1. Chemical Identity and Specifications Item Specification Product Name Glabridin CAS Number 59870-68-7 Molecular Formula C₂₀H₂₀O₄ Molecular Weight 324.37 g/mol Botanical Source Root of Glycyrrhiza glabra L. Appearance White to off-white crystalline powder Purity ≥98% (HPLC) Solubility Soluble in ethanol, DMSO; poorly soluble in water Documentation COA, HPLC, SDS, TDS available per batch Because Glabridin is a single purified compound rather than a standardized extract, buyers can verify identity and purity analytically with standard laboratory methods, which is one reason it is widely used in cosmetic raw-material and natural-product research programs. 2. Glabridin 98% vs. Standardized Licorice Extract: Know What You Are Comparing A frequent source of confusion in licorice-derived quotations is the difference between purified Glabridin and standardized licorice extract: Parameter Glabridin 98% (purified compound) Licorice extract (standardized, e.g. 40% Glabridin) Composition Single isoflavan compound Complex extract with multiple licorice constituents Purity basis ≥98% Glabridin by HPLC Glabridin content standardized, balance is other extractives Typical use Cosmetic actives, analytical reference, research Finished-product formulations, cost-driven applications Price basis Per-kilogram, purity-driven Lower unit cost, higher inclusion rates Analytical identity Sharp single HPLC peak Multiple-peak fingerprint Before comparing quotations, confirm the basis: "98% Glabridin" and "40% Glabridin licorice extract" are not interchangeable, and neither price nor formulation math can be compared directly. 3. HPLC Verification: What a Valid COA Should Contain When auditing a supplier's Certificate of Analysis for Glabridin 98%, check for the following: 1. Batch-specific data. The COA must reference the exact batch number you will receive. Template COAs without batch numbers are a warning sign. 2. HPLC method and chromatogram. Ask for the actual chromatogram, not only the purity figure. The report should state the column type, detection wavelength, and integration method. 3. Identity confirmation. For high-value shipments, IR or MS confirmation of structure adds assurance that the compound is Glabridin rather than a co-eluting peak. 4. Impurity profile. Residual licorice congeners (e.g., glabrene, liquiritigenin) and process-related impurities should be reported or stated as within specification. 5. Heavy metals and residual solvents. Results should align with the requirements of your destination market — for example, the technical documentation expectations for cosmetic raw materials in the EU or North America. 6. SDS and TDS. Safety data and technical data sheets should be current and consistent with the COA. A practical approach used by many procurement teams: request a 20 g sample with full documentation, run independent HPLC verification at a third-party laboratory, then move to commercial quantities. CQ HERB supports sample evaluation with batch-specific documentation for this purpose. 4. Stability, Packaging and Storage Glabridin is sensitive to light and oxidation. In practice, this affects bulk handling: · Packaging: double-layer PE bags inside fiber drums for 1–25 kg quantities; sealed foil bags for smaller development batches. · Storage: cool, dry, light-protected conditions; keep containers tightly closed. · Shelf life: typically 24 months when stored as recommended; retest dates should appear on the COA. · Formulation note: because solubility in water is low, formulators commonly work with ethanol-based or solubilized systems; discuss the intended formulation format with your supplier so the recommended grade and particle presentation match. 5. Intended Applications and Regulatory Context Glabridin 98% is supplied for: · Cosmetic raw-material development — as a botanical-derived active ingredient used by formulators in skin-care product development, where the finished product's claims must comply with local cosmetic regulations. · Research applications — as a reference compound and research material in phytochemistry and natural-product studies. Regulatory note: the permitted use, labeling, and claim language for Glabridin-containing products differ by market (cosmetic ingredient frameworks, ingredient nomenclature such as INCI, and local advertising rules). Buyers should confirm the intended use and destination-market requirements with their own regulatory team. CQ HERB supplies the ingredient together with technical documentation; the ingredient itself is not a finished product and carries no product claims. 6. Supplier Evaluation Checklist Use this checklist when comparing Glabridin suppliers: · Batch-specific HPLC chromatogram provided (not just a purity number) · Botanical origin and extraction process described transparently · Heavy metals and residual solvents reported · SDS, TDS, and COA consistent with each other · Sample policy: small-quantity samples available for third-party verification · Traceable production information and stable multi-batch supply · Export documentation experience for your destination market · Responsive technical support (not only sales support) Nanjing Spring & Autumn Biological Engineering Co., Ltd. (CQ HERB) supplies Glabridin 98% with batch-based quality documentation including COA, HPLC analytical data, SDS and TDS, and supports sample evaluation before bulk orders. Our quality management system is certified to ISO 9001. 7. Bulk Ordering Practicalities · Sample stage: 20 g with full documentation for independent verification. · Development batches: 1–5 kg, typically ex-stock or short lead time. · Commercial quantities: 25 kg fiber drums; larger volumes scheduled against forecast. · Shipping: export-standard packaging; documentation set provided per shipment. · Lead time: confirm current stock and production schedule when requesting quotation. FAQ Q: What CAS number is Glabridin? A: Glabridin is CAS 59870-68-7, molecular formula C₂₀H₂₀O₄, molecular weight 324.37 g/mol. Q: Is Glabridin the same as licorice extract? A: No. Glabridin is a single purified compound isolated from licorice root. Licorice extract is a complex botanical preparation that may be standardized to a defined Glabridin content. Q: What purity grade should I buy? A: ≥98% HPLC is the common specification for cosmetic raw-material development and research use. Standardized licorice extracts (lower Glabridin content) are a separate product category with a different cost structure. Q: Which documents should a Glabridin supplier provide? A: At minimum: batch COA, HPLC chromatogram, SDS, TDS, botanical source statement, and heavy-metal/residual-solvent data as applicable to your market. Q: Can I get a sample before bulk purchase? A: Yes. CQ HERB provides sample quantities with batch-specific documentation so buyers can complete independent verification before commercial orders. Q: How should Glabridin be stored? A: In cool, dry, light-protected conditions in tightly closed containers. Refer to the SDS and TDS for batch-specific guidance.

Psoralen is a naturally occurring furanocoumarin associated with several botanical sources, including Psoralea corylifolia. For laboratories, ingredient developers, and specialty raw material buyers, sourcing high-purity Psoralen requires more than checking a purity percentage on a product page. Chemical identity, analytical methods, batch documentation, safe handling, and supplier communication all deserve careful review. This guide explains how to evaluate Psoralen 98%, interpret its chemical specifications, review HPLC and Certificate of Analysis (COA) information, and prepare a more effective bulk sourcing inquiry.   Quick Answer: How Do You Choose a Psoralen 98% Supplier? When sourcing Psoralen 98%, start by confirming the required chemical identity, CAS number, purity specification, and intended use. Then review the supplier's analytical method, batch-specific COA, available safety documentation, packaging, storage recommendations, and commercial terms. A supplier's stated purity is only one part of the evaluation. Buyers should understand how the assay was measured, whether the results relate to the actual batch, and whether additional quality or safety requirements apply to their project. Before placing a bulk order, confirm the minimum order quantity, sample availability, lead time, destination requirements, and the documents that can actually be supplied. Key Takeaways Confirm chemical identity: Match the product name, CAS number, molecular formula, and specification to your project requirements. Understand the purity claim: Confirm the acceptance limit, assay method, and reporting basis behind the stated 98% grade. Review batch documentation: Check that the COA identifies the material and includes relevant test methods, specifications, and results. Evaluate safety requirements: Psoralen is a photoreactive compound; review the current SDS and applicable handling precautions before use. Compare suppliers consistently: Evaluate technical suitability, documentation, price, packaging, lead time, and communication together. Plan for bulk purchasing: Define quantity, destination, required documents, and acceptance criteria before requesting a formal quotation. 1. What Is Psoralen? Psoralen is a naturally occurring furanocoumarin, a class of compounds characterized by a fused furan and coumarin structure. It has been identified in certain plants, including Psoralea corylifolia, also known as Cullen corylifolium in some botanical classifications. Psoralen is of interest in natural product chemistry, analytical research, and studies of photochemical behavior. Its chemical properties and interaction with ultraviolet radiation also make appropriate safety assessment important when handling the compound. Psoralen should not be confused with Isopsoralen, also known as Angelicin. Although these compounds belong to the broader furanocoumarin family and may be associated with related botanical sources, they are chemically distinct substances. Buyers should verify the exact compound required rather than relying on botanical association or a similar product name. Basic Chemical Information Property Information Product name Psoralen CAS number commonly listed 66-97-7 Molecular formula C₁₁H₆O₃ Molecular weight Approximately 186.16 g/mol Chemical class Furanocoumarin Botanical association Psoralea corylifolia and other reported plant sources Commercial grade discussed 98% Analytical verification Confirm the method and current product specification with the supplier Chemical identity information should be checked against a recognized chemical database and the supplier's current product documentation before ordering. 2. What Does Psoralen 98% Mean? Psoralen 98% generally refers to a commercial grade with a stated assay or purity target of 98%. However, a percentage should not be interpreted without understanding the specification and analytical method behind it. Before comparing supplier quotations, clarify the following: Does 98% represent the minimum acceptance limit or a representative assay result? Is the result reported on an as-is basis or a dry basis? Which analytical technique and calculation procedure are used? Is the result associated with the actual batch being offered? Are other quality attributes assessed separately? Does the specification match the intended research or ingredient-development application? Purity and overall quality are related but different concepts. An assay result alone does not establish the complete impurity profile, residual-solvent status, contaminant levels, stability, or suitability for a particular finished formulation. Psoralen 98% Versus Psoralea corylifolia Extract Comparison point Psoralen 98% Psoralea corylifolia extract Material type High-purity individual compound Botanical extract containing multiple constituents Composition Primarily Psoralen according to the stated specification Varies with source material and extraction process Main quality focus Identity, assay, and relevant impurity controls Botanical identity, extract specifications, and marker content Documentation priorities COA, analytical method, and batch traceability Botanical source, extraction details, standardization, and batch results Purchasing considerations Required grade, analytical evidence, and quantity Extract ratio or standardization target, application, and source details These products are not interchangeable. Select the material that matches the actual project specification, and do not assume that an extract standardized to a botanical marker is equivalent to an isolated compound. 3. How to Verify Psoralen Identity and CAS Information Identity verification is an essential step in the procurement of high-purity compounds. A mismatch between the requested compound and the material supplied can cause problems in analytical work, internal quality review, and formulation development. Before ordering, confirm that the following details are consistent across the quotation, product specification, COA, product label, and supporting analytical records: Product name and relevant synonyms. CAS number required by the project. Molecular formula and molecular weight, where applicable. Purity grade and assay acceptance criteria. Batch or lot number. Analytical method and reporting basis. Document revision and relevant dates. Psoralen Versus Isopsoralen Psoralen and Isopsoralen (Angelicin) are distinct compounds. Similar botanical associations do not make them interchangeable, and the CAS number should be used as one element of identity verification. When purchasing either material, ask the supplier to confirm the exact compound name and match it to the specification and batch documentation. If your internal chemical database identifies a discrepancy, resolve it before ordering. 4. How to Evaluate HPLC Results for Psoralen HPLC is commonly used for the assay and chromatographic evaluation of many high-purity botanical compounds. However, the statement “HPLC tested” does not by itself establish that two products have equivalent analytical quality. What Should Buyers Check? 1. Analytical method Ask which method was used to determine the stated assay and whether it is appropriate for the intended measurement. 2. Method conditions Where relevant and available, review the sample preparation, chromatographic conditions, detector, calculation procedure, and reporting basis. 3. Chromatographic evidence If a chromatogram is provided, check whether it identifies the relevant peak and contains enough information for the intended technical review. A chromatogram is supporting evidence, not proof of every quality attribute. 4. Batch traceability Confirm that the result belongs to the quoted or supplied batch. A generic product specification and a batch-specific COA serve different purposes. 5. Additional quality requirements Depending on the project, further tests may be needed to evaluate related compounds, residual solvents, contaminants, or other acceptance criteria. Requirements should be agreed with the supplier before purchase. Why Method Consistency Matters Results from different analytical methods may not be directly comparable. Differences in sample preparation, detection, calculation, or reporting basis can affect how an assay result should be interpreted. For supplier qualification, compare like with like: use a defined specification, understand the method behind the reported percentage, and arrange independent testing when the project's risk or quality requirements justify it.   5. What Should a Psoralen COA Include? A Certificate of Analysis records test results for an identified batch against defined specifications. Its value depends on whether the document is traceable, relevant, and sufficiently detailed for the buyer's quality review. COA item What buyers should check Product name Does it match the ordered compound? Batch or lot number Can the tested material be traced to the supplied batch? Test items Are the required quality attributes included? Specification or limit Is the acceptance criterion clearly stated? Test method Is the method identified where needed? Result Is the result clear and interpretable? Test or issue date Is the document appropriate for the batch under review? Release information Is the document appropriately authorized by the supplier? The exact content depends on the material specification and supplier's quality system. A COA should be reviewed together with other documents where required. COA, TDS, and SDS: Understanding the Difference COA (Certificate of Analysis): Records analytical results for an identified batch. TDS or product specification: Describes product characteristics, technical information, and applicable acceptance criteria. SDS (Safety Data Sheet): Provides safety, handling, storage, exposure-control, and emergency-response information. These documents serve different purposes. Buyers should request the documentation relevant to their intended use and confirm availability before placing an order. 6. Safety, Handling, and Storage Considerations Psoralen is a photoreactive furanocoumarin. Its interaction with ultraviolet radiation is an important consideration in laboratory safety and handling. Buyers should not assume that a natural origin makes the compound inherently safe. Before handling the material: Review the current SDS and the supplier's handling instructions. Use the personal protective equipment and engineering controls specified by the relevant safety assessment. Avoid unintended exposure and follow applicable precautions regarding ultraviolet light. Keep the material in its specified container and follow the supplier's storage recommendations. Confirm any special packaging, transport, or disposal requirements with the appropriate safety personnel. Storage conditions should be based on the current product specification and supporting stability information. Do not assume a universal temperature, shelf life, or storage protocol without product-specific evidence. For cosmetic, pharmaceutical, food, or other regulated applications, buyers must independently confirm applicable regulatory status and suitability. Supplying a high-purity raw material does not automatically establish authorization for a particular use. 7. How to Choose a Reliable Psoralen Supplier A competitive price is useful, but supplier qualification should consider technical suitability, document quality, safety communication, and commercial reliability together. Supplier Evaluation Checklist Product and technical fit Can the supplier confirm the exact compound and CAS number? Is the requested purity grade clearly specified? Is the analytical method identified? Are the available results and documents suitable for your evaluation? Quality and documentation Does the COA identify the relevant batch? Are the test items and acceptance criteria clear? Can the supplier provide an SDS and relevant technical documentation? Are product claims supported by current records? Commercial capability What sample sizes and bulk quantities are available? What are the minimum order quantity and packaging options? What is the expected lead time? Are shipping terms and destination requirements clear? Can repeat orders be reviewed against an agreed specification? Communication Does the supplier answer technical questions clearly? Can discrepancies in documentation be resolved before purchase? Are quotations and product descriptions consistent with the available evidence? Questions to Ask Before Ordering What Psoralen grade and assay specification are available? Can you confirm CAS 66-97-7 in the current product documentation? Which analytical method is used for the purity assay? Can you provide the current specification and an appropriate COA? Is an HPLC chromatogram available for the offered batch? What sample quantities, MOQ, and bulk packaging options are available? Which SDS and additional technical documents can be supplied? What are the estimated lead time and shipping options for my destination? A structured inquiry helps buyers compare suppliers on a consistent basis and reduces misunderstandings before an order is placed. 8. Bulk Purchasing: What to Confirm Before Ordering Psoralen 98% Bulk sourcing requires agreement on the product specification, quantity, batch documentation, packaging, delivery arrangements, and acceptance criteria. Sample Evaluation For an initial evaluation, confirm sample size, sample cost, shipping cost, dispatch time, and available documentation. If independent testing is planned, agree on the analytical method and acceptance criteria in advance. This approach makes the results easier to interpret and provides a clearer basis for deciding whether to proceed with a larger order. Bulk and Repeat Orders Before confirming a bulk purchase, clarify: Required quantity and packaging format. Whether the quoted material is in stock or requires production. Batch availability and estimated lead time. Applicable specification and required documentation. Shipping terms, destination, and freight arrangements. Requirements for reviewing future batches. For repeat procurement, use a written specification and a consistent batch-review process rather than relying solely on an earlier quotation or product description. Information to Include in a Bulk Inquiry To receive a more relevant quotation, provide: Product: Psoralen Required grade: for example, 98%, subject to the agreed specification CAS number: 66-97-7, subject to project verification Quantity: sample, grams, kilograms, or planned annual demand Intended research or ingredient-development application Destination country Required analytical method or documentation Target delivery date, if applicable Clear requirements help the supplier assess whether the offered material matches the project's technical and commercial needs. 9. Psoralen 98% from CQHERB CQHERB supplies botanical raw materials and high-purity compounds for business customers involved in research, analytical work, and ingredient development. For buyers evaluating Psoralen 98%, CQHERB can discuss the requested specification, quantity, available product information, and applicable purchasing arrangements. Before confirming an order, buyers should communicate their required compound identity, assay specification, intended application, destination, and documentation needs. The proposed material and available batch records should then be reviewed against those requirements. For Psoralen sourcing inquiries, contact CQHERB: Company: Nanjing Spring & Autumn Biological Engineering Co., Ltd. Email: sale05@cqherb.com Website: https://www.cqherb.com/ Product information: https://www.cqherb.com/products Please include your required grade, quantity, destination country, and analytical or documentation requirements in your inquiry. 10. Frequently Asked Questions About Psoralen 98% What is the CAS number of Psoralen? CAS 66-97-7 is commonly listed for Psoralen. Confirm the identity against a recognized chemical database and the supplier's current product documentation before ordering. What does Psoralen 98% mean? It generally describes a commercial grade with a stated assay or purity target of 98%. Buyers should verify the acceptance limit, method, reporting basis, and batch result. Is Psoralen the same as Isopsoralen? No. Psoralen and Isopsoralen (Angelicin) are distinct chemical compounds. Buyers should confirm the exact identity and CAS number required for their project. Should I request HPLC data before purchasing? If analytical verification is important to your project, ask which method is used and what supporting data are available. Review the results against your own specification rather than relying on a generic “HPLC tested” statement. What documents should I request from a Psoralen supplier? Commonly requested documents include a product specification or TDS, a batch-specific COA when available, and an SDS. Additional analytical or quality documents may be necessary depending on the project. Can I buy Psoralen in bulk? Bulk availability, minimum order quantity, packaging, lead time, and pricing depend on the supplier's current offering and the required specification. Provide the quantity and destination to request a relevant quotation. What safety precautions are important for Psoralen? Psoralen is photoreactive, so buyers should review the current SDS and follow the applicable handling and exposure precautions. The exact controls should be determined by the material documentation and the user's safety assessment. How can I request a Psoralen quotation from CQHERB? Email sale05@cqherb.com with the required grade, quantity, destination country, and technical documentation needs. CQHERB can review the inquiry and confirm the relevant product and commercial details. Conclusion Sourcing Psoralen 98% requires a structured evaluation of chemical identity, purity specifications, analytical evidence, safety documentation, and commercial supply arrangements. For buyers comparing suppliers, the best starting point is a clearly defined specification supported by relevant batch information. Confirm the technical requirements before ordering samples or bulk material, and ensure that the offered compound matches the intended project. For Psoralen sourcing inquiries, contact CQHERB at sale05@cqherb.com. References CQHERB product catalog: https://www.cqherb.com/products PubChem chemical database: https://pubchem.ncbi.nlm.nih.gov/ Supplier product specification and SDS for the specific Psoralen grade offered. Note: Public chemical references provide background information. Product-specific assay results, storage conditions, shelf life, safety instructions, and document availability should be confirmed against current supplier documentation before purchase.

Cycloastragenol 98% Supplier: Purity, CAS Identity, COA & Bulk Buying Guide Cycloastragenol is a high-value botanical compound of interest to natural product researchers, ingredient developers, and specialty raw material buyers. When sourcing Cycloastragenol 98%, buyers need to look beyond the purity figure on a product listing. Chemical identity, assay methodology, batch documentation, supply consistency, and supplier communication all matter when qualifying a material for further evaluation. This guide explains how to evaluate Cycloastragenol 98%, what to review in a Certificate of Analysis (COA), how to prepare a bulk sourcing inquiry, and which questions to ask before placing an order. Quick Answer: How Do You Choose a Cycloastragenol 98% Supplier? To evaluate a Cycloastragenol 98% supplier, confirm the intended chemical identity and CAS number, request the current product specification and batch-specific COA, review the analytical method used to determine purity, and confirm the available quantity, packaging, storage recommendations, lead time, and shipping terms. A listing that states “98% purity” is only a starting point. Buyers should understand how the assay result was obtained and whether the documentation corresponds to the exact material being offered. For bulk purchasing, request written confirmation of the grade, minimum order quantity, available stock, sample options, and documentation before making a purchasing decision. Key Takeaways Confirm chemical identity: Match the product name, CAS number, molecular formula, and specification to the material required for your project. Review the assay method: A purity percentage should be interpreted together with its analytical method and reporting basis. Request batch-specific documentation: A COA should identify the batch and show the relevant test items, methods, acceptance criteria, and results. Separate purity from overall quality: Purity alone does not establish the complete impurity profile, contaminant status, or suitability for a particular application. Evaluate supply capability: Confirm sample availability, bulk quantities, packaging, lead time, and repeat-order arrangements. Define the intended application: Research, ingredient development, and commercial formulation projects may have different documentation and quality requirements. 1. What Is Cycloastragenol? Cycloastragenol is a triterpenoid sapogenin associated with Astragalus-derived natural products. It is described in chemical databases as an aglycone related to astragaloside IV. The compound is of interest in natural product chemistry and research involving botanical constituents. For ingredient buyers, its value begins with establishing the correct chemical identity and obtaining material that meets a clearly defined specification. Cycloastragenol should not be confused with Astragalus root powder, an Astragalus extract, or an astragaloside-standardized extract. These materials have different compositions and cannot be treated as interchangeable solely because they are associated with the same botanical source. Cycloastragenol: Basic Chemical Information Property Information Product name Cycloastragenol Common abbreviation CAG CAS number commonly listed 78574-94-4 Molecular formula C₃₀H₅₀O₅ Molecular weight Approximately 490.72 g/mol Chemical class Triterpenoid sapogenin Botanical association Astragalus species Commercial grade discussed in this guide 98% Analytical documentation Confirm the current specification and available batch records with the supplier Public chemical references list Cycloastragenol under CAS 78574-94-4, with molecular formula C₃₀H₅₀O₅ and a molecular weight of approximately 490.72 g/mol. Buyers should independently verify the identity required for their project and ensure that the supplier's documentation matches it. Reference: PubChem, Cycloastragenol. https://pubchem.ncbi.nlm.nih.gov/compound/13943286 2. What Does Cycloastragenol 98% Mean? Cycloastragenol 98% generally indicates a material grade with a stated assay or purity target of 98%. However, the meaning of that number depends on the specification and analytical procedure used. Before comparing quotations, buyers should clarify the following: Is 98% the minimum acceptance limit or a representative result? Is the result reported on an as-is basis or a dry basis? Which analytical technique is used? What are the applicable test conditions and calculation method? Does the reported value come from the actual batch being supplied? Are relevant impurities and other quality attributes evaluated separately? A reported assay result should not automatically be interpreted as proof of every aspect of material quality. For example, a purity result does not by itself establish compliance with microbiological limits, residual-solvent requirements, heavy-metal specifications, or the requirements of a particular finished product. 98% Purity Versus a Standardized Astragalus Extract Comparison point Cycloastragenol 98% Standardized Astragalus extract Product type High-purity individual compound Botanical extract with a defined standardization target Composition Intended to be predominantly Cycloastragenol Contains a mixture of botanical constituents Main specification focus Compound identity and assay Botanical identity, extract specifications, and marker content Documentation priorities Identity, assay method, batch results Botanical source, extract details, marker assay, and batch results Purchasing considerations Analytical verification and required quantity Standardization level, source material, extraction details, and intended use These product types serve different procurement purposes. Buyers should select the material based on the actual project specification rather than comparing their prices or percentages as if they represented the same product. 3. How to Verify Cycloastragenol Identity and CAS Information Chemical identity is a basic requirement when sourcing a high-purity compound. A mismatch in product name, CAS number, or specification can create problems during laboratory evaluation, internal quality review, and purchasing approval. Before ordering, check that the following information is consistent across the quotation, product specification, COA, product label, and any supporting analytical records: Product name and relevant synonyms. CAS number required by the buyer. Molecular formula and molecular weight, where applicable. Stated purity grade and assay acceptance criteria. Batch number and document revision details. Analytical method and reporting basis. If a buyer's internal specification or database lists a different CAS number, do not assume that the discrepancy is unimportant. Ask the supplier and the buyer's technical team to resolve the identity requirement before purchase. The same principle applies to product descriptions that use terms such as “natural,” “botanical,” or “high purity.” Such terms do not replace the need for clear identity and quality documentation. 4. How to Evaluate HPLC and Other Analytical Data Analytical data are important when comparing Cycloastragenol suppliers. However, the phrase “HPLC tested” does not fully describe a method or establish that two suppliers' results are directly comparable. What Buyers Should Review 1. Analytical technique Ask which technique was used for the assay and whether the method is appropriate for the compound and the intended measurement. Depending on the analytical characteristics of a substance, the detection system and sample preparation can affect the result. 2. Method details Where available and appropriate, review the method reference, column, mobile phase, detector, sample preparation, and calculation procedure. Do not assume that every supplier uses the same method simply because both report an HPLC result. 3. Chromatographic evidence When chromatograms are available, check whether the report identifies the relevant peak and provides enough information for the intended review. A chromatogram is supporting evidence, not an automatic guarantee of identity or complete impurity characterization. 4. Batch traceability Confirm that the analytical report relates to the batch quoted or supplied. A generic specification sheet and a batch-specific COA serve different purposes. 5. Independent verification For projects requiring stronger supplier qualification, buyers may arrange independent testing using an agreed method and acceptance criteria. Why Assay Methods Matter Results from different analytical methods may not be directly comparable. A sound supplier evaluation therefore considers both the reported number and the procedure used to obtain it. For Cycloastragenol, buyers with demanding analytical requirements should discuss method suitability and the available supporting evidence with the supplier before relying on a percentage figure alone. CQHERB recommends that customers communicate their required assay method or internal specification at the inquiry stage so that the proposed material and available documentation can be evaluated against the project's needs. 5. What Should a Cycloastragenol COA Include? A Certificate of Analysis (COA) records the test results for a particular material or batch against defined specifications. Its usefulness depends on whether it clearly identifies the material and documents the relevant quality checks. When reviewing a Cycloastragenol COA, buyers should look for the following information where applicable: COA item What to check Product name Does it match the ordered material? Batch or lot number Can the tested material be traced to the supplied batch? Test item Are the required quality attributes listed? Specification or acceptance limit Is the criterion clearly stated? Test method Is the method identified where needed? Result Is the reported result clear and interpretable? Test or issue date Is the document current for the batch under review? Authorized release information Is the document appropriately approved by the supplier? The exact content of a COA varies by product specification and supplier quality system. Additional documents may be needed depending on the intended market, application, and buyer qualification procedure. COA, Specification Sheet, and SDS: What Is the Difference? COA: Records analytical results for an identified batch. Product specification or TDS: Describes defined product attributes, acceptance criteria, and technical information. SDS: Provides safety information relevant to handling, storage, exposure control, and emergency response. These documents are complementary rather than interchangeable. Buyers should request the documents relevant to their project and confirm availability before placing an order. 6. How to Choose a Reliable Cycloastragenol Supplier A competitive price is useful, but it should not be the only factor in supplier selection. Buyers need to assess whether the offered material, documentation, and supply arrangements meet their requirements. Supplier Qualification Checklist Product and technical fit Can the supplier confirm the exact product identity and required grade? Is the stated purity supported by an appropriate analytical method? Are the specification and available batch documents clear? Can the supplier explain any limitations in the offered grade? Commercial fit What quantities are available for evaluation and bulk purchasing? Is there a minimum order quantity? Are sample costs and freight quoted separately?   What are the packaging options and estimated lead time? Can the supplier discuss repeat-order availability? Documentation and communication Can the supplier provide the documents actually available for the offered batch? Are product claims consistent with the supporting records? Can the supplier clarify the proposed shipping terms and destination requirements? Is the supplier responsive to technical and purchasing questions? Questions to Ask Before Ordering For a more efficient qualification process, buyers can send a concise list of questions: What Cycloastragenol grade and assay specification are available? Which CAS number is stated in the product documentation? Which method is used for the purity assay? Can you provide the current specification and a representative or batch-specific COA, as appropriate? What sample quantities and bulk quantities can you supply? What are the MOQ, packaging, lead time, and shipping options? Which additional documents are available for the intended application? Clear answers help buyers compare suppliers on a like-for-like basis and reduce misunderstandings before an order is placed. 7. Buying Cycloastragenol in Bulk: What to Confirm Bulk procurement requires more than confirming the price per kilogram. The buyer and supplier should agree on the grade, quantity, batch documentation, delivery arrangements, and acceptance requirements. Small-Quantity Evaluation For initial evaluation, confirm the available sample size, sample price, freight cost, expected dispatch time, and documents that can accompany the sample. If the material will be tested by an external laboratory, agree on the test method and acceptance criteria before testing. This makes the results easier to interpret and compare. Bulk and Repeat Orders For larger purchases, confirm: Required quantity and packaging format. Whether the quoted material is currently in stock or subject to production. Batch availability and expected lead time. Applicable specification and documentation. Shipping terms, destination, and freight arrangements. How future batches will be reviewed against the agreed requirements. For repeat procurement, buyers should establish a written specification and a consistent batch-review process rather than relying only on the wording of an earlier quotation. Information to Include in a Bulk Inquiry To receive a more accurate quotation, provide the supplier with: Product: Cycloastragenol Required grade: for example, 98%, subject to the agreed specification CAS number required by your project Quantity: sample, grams, kilograms, or planned annual demand Intended application and relevant technical requirements Destination country Required documents or analytical method Target delivery date, if applicable The more clearly these requirements are defined, the easier it is for the supplier to determine whether the available material is a suitable match. 8. Cycloastragenol 98% from CQHERB CQHERB supplies botanical raw materials and high-purity compounds for B2B customers involved in ingredient sourcing, research, and formulation development. For buyers evaluating Cycloastragenol 98%, CQHERB can discuss the requested grade, order quantity, available product information, and applicable purchasing arrangements. Before confirming an order, buyers should communicate their required chemical identity, assay specification, quantity, destination, and documentation needs. The proposed material and the available batch records can then be reviewed against those requirements. To inquire about Cycloastragenol 98%, please contact CQHERB: Company: Nanjing Spring & Autumn Biological Engineering Co., Ltd. Email: sale05@cqherb.com Website: https://www.cqherb.com/ Please include your required quantity, destination country, and any specific analytical or documentation requirements in your inquiry. 9. Frequently Asked Questions About Cycloastragenol 98% What is the CAS number of Cycloastragenol? CAS 78574-94-4 is commonly listed for Cycloastragenol in public chemical references. Buyers should confirm that the CAS number in the supplier's documentation matches the exact identity required for their project. What does Cycloastragenol 98% mean? It generally describes a grade with a stated assay or purity target of 98%. Buyers should confirm the acceptance limit, analytical method, reporting basis, and batch result before comparing offers. Is a COA enough to verify Cycloastragenol quality? A COA is an important part of supplier qualification, but it should be reviewed alongside the product specification, analytical method, batch traceability, and any additional quality requirements relevant to the intended application. Should I request HPLC data before purchasing? If analytical verification is important to your project, ask which method is used and what supporting data are available. Review the method and results against your own technical requirements rather than relying on the term “HPLC tested” alone. What is the difference between Cycloastragenol and Astragalus extract? Cycloastragenol is an individual compound, whereas an Astragalus extract contains a mixture of botanical constituents. An extract standardized to a particular marker is not automatically equivalent to a high-purity Cycloastragenol product. Can I buy Cycloastragenol in bulk? Bulk availability, minimum order quantity, packaging, lead time, and pricing depend on the supplier's current offering and the requested grade. Send the required quantity and destination to obtain a quotation based on your needs. Which documents should I request from a supplier? Commonly requested documents include a product specification or TDS, a batch-specific COA when available, and an SDS. Other documents may be needed depending on the buyer's quality system, application, and destination market. How can I request a Cycloastragenol quotation from CQHERB? Email sale05@cqherb.com with your required grade, quantity, destination country, and analytical or documentation requirements. CQHERB can review the inquiry and confirm the relevant product and commercial details. Conclusion Selecting a Cycloastragenol 98% supplier requires a structured review of chemical identity, assay methodology, batch documentation, and commercial supply arrangements. For buyers comparing suppliers, the most useful starting point is a clear specification supported by relevant analytical information. Confirm the requirements before requesting samples or placing a bulk order, and ensure that the offered material matches the intended project. For Cycloastragenol 98% sourcing inquiries, contact CQHERB at sale05@cqherb.com. References PubChem. Cycloastragenol: chemical identity, molecular formula, and molecular weight. https://pubchem.ncbi.nlm.nih.gov/compound/13943286 Sigma-Aldrich. Cycloastragenol, ≥98% (HPLC): product information and listed chemical properties. https://www.sigmaaldrich.com/PA/en/product/sigma/sml1448 Note: Public chemical references provide background information. Product-specific specifications, analytical methods, batch results, and document availability should be confirmed with the supplier before purchase.

Licochalcone A 98%: Specifications & Bulk Sourcing Guide Quick Answer Licochalcone A is a naturally occurring chalcone-type flavonoid associated with licorice (Glycyrrhiza species). For buyers evaluating Licochalcone A 98% (CAS 58749-22-7), the key purchasing considerations include compound identity, HPLC assay, batch-specific quality documentation, physical characteristics, packaging, and supplier transparency. For B2B sourcing, a stated purity of 98% is only one part of the evaluation. Buyers should confirm the analytical method, review the Certificate of Analysis (COA), clarify the required specification, and ensure that the supplied material matches the intended research or ingredient-development application. CQHERB supplies Licochalcone A 98% for professional ingredient evaluation and research-related applications. Product-specific specifications, documentation availability, sample terms, and bulk quotation details should be confirmed directly with the supplier. Key Takeaways   Product identity: Licochalcone A, CAS 58749-22-7. Purity specification: 98%, with the assay method and acceptance criteria to be confirmed against the current product specification. Quality evaluation: Review the COA, analytical method, batch information, and any additional testing required for your project. Supplier qualification: Compare documentation, specification consistency, packaging, lead time, and communication quality—not just the quoted price. Bulk purchasing: Confirm MOQ, available quantity, packaging, delivery terms, and destination-specific shipping requirements before placing an order. 1. What Is Licochalcone A? Licochalcone A is a chalcone-type flavonoid found in licorice, particularly Glycyrrhiza inflata. It belongs to a broader group of plant-derived phenolic compounds investigated in natural-product chemistry and ingredient research. Basic chemical information Item Information Product name Licochalcone A CAS number 58749-22-7 Molecular formula C₂₁H₂₂O₄ Molecular weight Approximately 338.40 g/mol Compound class Chalcone-type flavonoid Botanical source Licorice, particularly Glycyrrhiza inflata Commercial specification discussed 98% Analytical approach HPLC assay, subject to the product's current specification These details identify the target compound but do not replace a batch-specific COA or a complete technical specification. Buyers should confirm the actual source material, assay basis, and analytical method for the lot being quoted. Why does compound identity matter? When sourcing plant-derived compounds, similar product names do not necessarily indicate equivalent materials. Different licorice species, extract grades, marker-compound concentrations, and purification levels can result in materially different specifications. Before comparing quotations, verify that each supplier is offering Licochalcone A itself at the required assay level, rather than a licorice extract standardized to a lower Licochalcone A content. 2. What Does Licochalcone A 98% Mean? A 98% specification generally indicates that the material is expected to meet a stated assay or purity criterion. However, the meaning of that figure depends on the analytical method, calculation basis, and acceptance criteria used by the supplier. For a technically meaningful comparison, buyers should establish: Whether 98% is the stated HPLC assay specification. Whether the result is calculated on an as-is or dry basis. Which analytical method and reference standard are used, where applicable. What acceptance range is specified for the delivered batch. Whether the COA reports an actual result or only a specification limit. An HPLC result should be interpreted in the context of the method and report. A chromatographic area percentage, for example, is not automatically equivalent to a mass-based assay unless the analytical procedure supports that interpretation. 98% purified compound versus standardized licorice extract A high-purity compound and a standardized botanical extract serve different purchasing purposes. Evaluation point Licochalcone A 98% Standardized licorice extract Main specification High assay of the target compound Defined marker-compound content Composition Primarily the specified compound, subject to the specification A mixture of botanical constituents Documentation focus Identity, assay, impurity profile where available Marker assay, extract specifications, and botanical information Purchasing priority Confirm identity and analytical evidence Confirm marker concentration and overall extract specification Suitable comparison Other materials meeting the same compound and assay requirements Other extracts with comparable marker content and specifications The two categories should not be treated as interchangeable. Select the material according to the technical requirements of the intended project. 3. How to Evaluate Licochalcone A 98% Quality A reliable purchasing assessment goes beyond the product name and headline purity. 3.1 Review the Certificate of Analysis The COA should identify the product and batch and report the tests relevant to the agreed specification. When reviewing a COA, check the following: Product name and CAS number. Batch or lot number. Manufacturing date and retest or expiry information, as applicable. Test items, methods, specifications, and actual results. Assay or purity result and its stated basis. Appearance and other agreed physical tests. Authorized review or approval, where applicable. If an item is not tested or reported, ask the supplier whether additional testing is available. Do not assume that every supplier tests every parameter. 3.2 Check the HPLC evidence For a product specified at 98% by HPLC, the chromatographic method is an important part of the quality assessment. Depending on the project's requirements, buyers may request: The HPLC assay method or a method summary. A representative chromatogram or batch-specific chromatographic data.   Details of the reference standard and calculation approach, where available. Clarification of how the reported result relates to the product specification. A chromatogram can support an analytical assessment, but it should be interpreted alongside the method and the corresponding COA. It should not be presented as proof of every aspect of product quality. 3.3 Confirm additional quality requirements Depending on the intended application and buyer's quality system, additional tests may be relevant. Quality area What buyers should clarify Identity Which identity tests are performed and what evidence is available? Assay What method and acceptance criteria define the stated purity? Related substances Is an impurity profile required for the project? Residual solvents Are limits and test reports required? Elemental impurities Are specific limits or test results required? Microbiological quality Is testing necessary for the intended material and application? Stability What storage conditions and retest or shelf-life information are supported? These are supplier-qualification questions, not claims that every test is included in every CQHERB order. Confirm the current product specification and document availability before purchase. 4. How to Choose a Licochalcone A Supplier For overseas B2B buyers, supplier selection should consider technical suitability, documentation, commercial terms, and supply reliability together. Step 1: Match the specification Provide the target compound, required assay, analytical method requirements, and any additional acceptance criteria. This helps prevent comparisons between products that have similar names but different compositions. Step 2: Evaluate documentation Ask for the current product specification and a representative or batch-specific COA, subject to availability and the supplier's document-sharing policy. Determine whether other documents are needed for your internal quality review. Step 3: Confirm the quantity and packaging Request a quotation for the actual evaluation or production quantity. Confirm available stock, MOQ, packaging format, and whether the supplier can accommodate the required order size. Step 4: Clarify sample arrangements For initial evaluation, confirm the sample quantity, price, shipping cost, destination requirements, and expected dispatch time. A sample should be assessed against the same critical specifications expected for a subsequent production order. Step 5: Review the commercial terms Before issuing a purchase order, clarify: Unit price and quotation validity. MOQ and price breaks, if available. Incoterms and the named delivery location. Shipping method, freight charges, and estimated lead time. Payment terms. Documentation supplied with the order. A low unit price may not represent the best overall purchasing option if the specification, documentation, or delivery arrangements do not meet project requirements. 5. What Information Should You Include in a Bulk Quotation Request? A complete inquiry allows the supplier to respond more accurately and reduces unnecessary email exchanges. We recommend including the following information in your request: Information Example or guidance Product Licochalcone A CAS number 58749-22-7 Required specification 98% or your project-specific assay requirement Quantity Sample, evaluation quantity, or commercial order quantity Application Research, ingredient evaluation, or formulation development Required documents COA, specification, SDS, or other agreed documents Destination Country and delivery city Delivery preference Preferred Incoterm or shipping method Additional requirements Specific analytical tests, packaging, or quality criteria Providing the destination and required quantity is especially helpful when comparing total landed costs or evaluating shipping options. 6. Technical Considerations for Handling and Storage Storage and handling conditions should be based on the current product specification and supporting stability information. Before use, buyers should confirm the recommended storage temperature, protection from light and moisture, packaging requirements, and stated shelf life or retest period. For laboratory evaluation, use appropriate handling procedures and consult the relevant safety documentation. Solubility, formulation compatibility, and stability should be evaluated under the conditions of the intended system rather than inferred from the compound name alone. Where a project has defined temperature, solvent, or stability requirements, communicate those requirements before ordering so the supplier can assess whether the available material is suitable for evaluation. 7. About CQHERB's Licochalcone A 98% Supply CQHERB offers Licochalcone A 98% (CAS 58749-22-7) for professional research and ingredient-development inquiries. For a quotation or technical review, buyers can contact CQHERB to confirm: Current product specification and available quantity. COA and HPLC documentation availability. Additional testing or technical-document requirements. Sample arrangements and shipping costs. MOQ, bulk pricing, packaging, and lead time. The suitability of a particular lot should be assessed against the buyer's own specifications and intended application. Final supply terms and document availability should be confirmed before an order is placed. Explore the product page: Licochalcone A 98% | High Purity Licorice Flavonoid for Research Request Technical Information or a Bulk Quotation If you are evaluating Licochalcone A 98% for a research project or ingredient-development program, please share your required specification, quantity, destination country, and documentation needs. CQHERB can then review your requirements and confirm the available product information, sample terms, and quotation details. Contact: sale05@cqherb.comWebsite: https://www.cqherb.com/ Frequently Asked Questions 1. What is the CAS number of Licochalcone A? The CAS number used for Licochalcone A is 58749-22-7. Buyers should verify the compound identity against the supplier's current specification and supporting documentation. 2. What does Licochalcone A 98% mean? It refers to material specified at 98% assay or purity under a defined analytical method. The exact meaning depends on the method, calculation basis, and acceptance criteria. Request the current specification and COA to confirm the details. 3. Is Licochalcone A 98% the same as licorice extract? Not necessarily. A high-purity Licochalcone A material is different from a botanical extract standardized to a lower marker-compound concentration. Confirm the composition and assay before comparing products. 4. Which documents should I request before purchasing? Start with the product specification and COA. Depending on your quality requirements, you may also need SDS, HPLC data, identity evidence, or additional analytical reports. Confirm which documents are available for the specific product and batch. 5. Can I request a sample before placing a bulk order? Sample availability, quantity, price, and shipping arrangements should be confirmed with the supplier. Include your destination country and intended evaluation quantity when making an inquiry. 6. What information is needed for a bulk quotation? Provide the required assay, quantity, destination, packaging preferences, delivery terms, and any specific documentation or testing requirements. This allows the supplier to prepare a more relevant quotation. 7. How should Licochalcone A 98% be stored? Follow the storage instructions in the current product specification and supporting stability information. Confirm the recommended temperature, packaging conditions, and shelf life or retest period for the material being purchased. 8. How do I compare two Licochalcone A suppliers? Compare compound identity, assay method, COA evidence, additional quality requirements, packaging, MOQ, lead time, delivery terms, and total cost. Use equivalent specifications when comparing quotations. Conclusion Sourcing Licochalcone A 98% requires more than checking a purity figure or comparing unit prices. A sound purchasing decision starts with verified compound identity, a clearly defined analytical specification, appropriate quality documentation, and transparent commercial terms. By evaluating these factors before ordering, research teams, ingredient developers, and procurement professionals can make a more informed supplier comparison. For product-specific information, sample arrangements, or a bulk quotation, contact CQHERB with your required specification and quantity.     References and Further Reading CQHERB: Licochalcone A 98% Product Page CQHERB: Bulk Licochalcone A 98% Powder — Product and Quality Information This article is intended for professional ingredient sourcing and technical evaluation. Product specifications, analytical results, document availability, and commercial terms should be confirmed for the relevant batch. Research findings should not be interpreted as proof of finished-product efficacy or regulatory approval.

Astragalus Extract Cycloastragenol: A Growing Botanical Active for Healthy-Aging and Longevity Research Quick Answer Cycloastragenol is a naturally occurring triterpenoid sapogenin associated with Astragalus species, particularly Astragalus membranaceus. It is closely related to astragaloside compounds and has attracted scientific interest because of its reported effects on telomerase activity and cellular aging-related pathways.  In the United States, Cycloastragenol occupies an interesting position between botanical research, nutraceutical ingredients, healthy-aging products and longevity-focused formulations. The U.S. market already shows commercial and research activity around Cycloastragenol. Major scientific suppliers including Sigma-Aldrich, TCI America, Cayman Chemical and distributors such as VWR list Cycloastragenol for research and natural-product applications. Consumer-facing U.S. products also market Cycloastragenol as a longevity- and telomere-oriented ingredient. For B2B buyers, however, the most important question is not simply whether a supplier offers “Cycloastragenol 98%.” Buyers should evaluate chemical identity, purity, analytical method, botanical source, batch consistency, COA documentation, heavy metals, residual solvents, microbiological specifications and regulatory positioning. For manufacturers and ingredient distributors looking to enter the U.S. healthy-aging market, high-purity Cycloastragenol derived from Astragalus is a specialized botanical ingredient with applications spanning research, nutraceutical development and longevity-oriented product concepts.     Key Takeaways · Cycloastragenol is a triterpenoid sapogenin associated with Astragalus. · It is particularly associated with Astragalus membranaceus research. · Cycloastragenol is structurally related to Astragalus saponins, including astragaloside compounds. · Telomerase activation is one of the most important research areas surrounding Cycloastragenol. · Preclinical studies have investigated Cycloastragenol in cellular aging, oxidative stress, immune-cell function and other biological pathways. · U.S. scientific suppliers already offer Cycloastragenol, including ≥98% HPLC products. · U.S. consumer products also demonstrate commercial interest in Cycloastragenol as a healthy-aging ingredient. · FDA records show that a concentrated Astragalus extract containing >95% Cycloastragenol was the subject of a U.S. New Dietary Ingredient notification in 2010. This does not mean that FDA approved Cycloastragenol as a drug or dietary ingredient; NDI notifications have specific regulatory meanings. · Product identity should be verified carefully because different databases and suppliers may associate Cycloastragenol with different CAS numbers. · For B2B buyers, purity + analytical documentation + batch consistency are more meaningful than a simple “98%” marketing statement.     1. What Is Cycloastragenol? Cycloastragenol is a naturally occurring pentacyclic triterpenoid and sapogenin associated with the roots of Astragalus species. It is particularly relevant to research involving Astragalus membranaceus, a botanical traditionally used in Asian herbal medicine. Chemically, Cycloastragenol is closely associated with Astragalus triterpene saponins. PubChem describes it as an aglycone derivative of astragaloside IV and identifies it as a pentacyclic triterpenoid sapogenin. Typical chemical information includes: Property Cycloastragenol Common Name Cycloastragenol Botanical Source Astragalus species Key Source Astragalus membranaceus Chemical Class Pentacyclic triterpenoid Category Sapogenin Molecular Formula C₃₀H₅₀O₅ Molecular Weight 490.72 g/mol Physical Form Powder Common Research Purity ≥98% HPLC Commercial research suppliers in the U.S. market list Cycloastragenol at ≥98% HPLC, demonstrating that high-purity material is already established within the research-chemical supply chain.     2. Cycloastragenol and Astragalus Extract: What Is the Difference? This distinction is particularly important for B2B buyers. Astragalus Extract is a botanical extract containing multiple naturally occurring constituents. Cycloastragenol is a specific purified triterpenoid constituent associated with Astragalus. Therefore, the terms should not be used interchangeably. Astragalus Extract A standardized Astragalus extract may contain: · Astragalosides · Polysaccharides · Flavonoids · Saponins · Other botanical constituents Cycloastragenol Cycloastragenol represents a more specifically defined chemical constituent. This makes it more appropriate when a formulation or research project requires: · defined chemical identity · high-purity active material · analytical quantification · reproducible experimental conditions · controlled concentration · mechanistic research For this reason, CQHERB can position the product not simply as an ordinary Astragalus root extract, but as a specialized high-purity Astragalus-derived active ingredient.     3. Why Is Cycloastragenol Attracting Attention in the U.S.? The U.S. market shows interest in Cycloastragenol from several different directions. 3.1 Research Chemical Market Cycloastragenol is already available through major U.S.-facing scientific suppliers. For example: · Sigma-Aldrich lists Cycloastragenol ≥98% HPLC. · TCI America lists Cycloastragenol as a research chemical. · Cayman Chemical offers Cycloastragenol for research use. · VWR lists multiple Cycloastragenol products from research suppliers. This creates a clear B2B opportunity for suppliers capable of offering: high purity + consistent batches + analytical documentation + competitive bulk pricing.     4. Cycloastragenol and the U.S. Healthy-Aging Market Beyond laboratory research, Cycloastragenol has become associated with the broader healthy-aging and longevity ingredient category. Current U.S. consumer products illustrate this positioning. For example, ProHealth Longevity markets a Cycloastragenol product at 10 mg per capsule and positions it around telomere and healthy-aging research. Other U.S.-market products emphasize: · telomere support · longevity · cellular health · healthy aging · antioxidant-related positioning · high-purity Cycloastragenol These commercial products demonstrate that Cycloastragenol is not limited to the laboratory-reagent market. Instead, it sits at the intersection of: Botanical Ingredients → Nutraceuticals → Healthy Aging → Longevity Research → Cellular Biology This makes Cycloastragenol particularly interesting for ingredient manufacturers and distributors targeting premium U.S. markets.     5. Cycloastragenol and Telomerase Research One of the most frequently studied characteristics of Cycloastragenol is its relationship with telomerase activity. Scientific research has reported that Cycloastragenol can stimulate telomerase activity in experimental systems. For example, research published in PubMed reported Cycloastragenol-associated telomerase activation in neuronal and cellular models. Another review described Cycloastragenol as a small-molecule telomerase activator and discussed its potential relevance to age-associated conditions, while also noting that further research is needed to clarify efficacy and potential adverse effects. This makes telomerase one of the most important scientific keywords associated with Cycloastragenol. Important distinction Telomerase research does not mean that a Cycloastragenol ingredient has been proven to reverse aging or extend human lifespan. For responsible B2B marketing, CQHERB recommends using language such as: “Cycloastragenol has been investigated for its effects on telomerase activity and cellular aging-related pathways.” rather than: “Cycloastragenol reverses aging.” This distinction is important for scientific credibility and regulatory risk management.     6. Emerging Research Areas Scientific literature has explored Cycloastragenol across multiple biological research areas. 6.1 Telomerase and Telomere Research This is currently one of the most recognizable research directions. Researchers have investigated: · telomerase activity · hTERT expression · telomere biology · cellular replicative capacity · aging-related cellular pathways     6.2 Oxidative Stress Research Research has also investigated the relationship between Cycloastragenol and oxidative stress pathways. A study reported that Cycloastragenol increased NRF2 nuclear localization and activity and affected downstream cytoprotective pathways in experimental models. This provides a scientific basis for investigating Cycloastragenol in: · oxidative stress research · cellular defense pathways · aging biology · NRF2-related research     6.3 Immune Cell Research Earlier research investigated Cycloastragenol-related telomerase activity and cellular function in human CD8+ T lymphocytes. Cayman Chemical's research documentation references work examining telomere loss, proliferative capacity and antiviral functions of CD8+ T cells. This area may be relevant to researchers studying: · immune-cell biology · T-cell function · cellular aging · telomere biology     6.4 Bone and Osteogenic Research Experimental studies have also examined Cycloastragenol in bone-related models. One study reported effects on osteogenic differentiation and mineralization through a telomerase-associated mechanism in cell and zebrafish models. This remains an area of preclinical research, rather than established clinical treatment.     7. U.S. Market Evidence: Is There Real Commercial Interest? Rather than relying on unsupported market-size estimates, several concrete indicators can be observed. Indicator 1: Major U.S. Research Suppliers Cycloastragenol is commercially listed by multiple established scientific suppliers serving the U.S. market. Examples include: · Sigma-Aldrich · TCI America · Cayman Chemical · VWR/Avantor distribution channels Indicator 2: U.S. Consumer Products Cycloastragenol is also sold in U.S.-market supplements positioned around longevity and healthy aging. Indicator 3: Historical U.S. Regulatory Activity FDA's public list of New Dietary Ingredient notifications includes a 2010 notification concerning a concentrated Astragalus membranaceus extract containing more than 95% Cycloastragenol for TA-65®. This is an important historical market signal because it shows that Cycloastragenol-rich Astragalus ingredients have been considered within the U.S. dietary-ingredient regulatory framework. However, an NDI notification should not be described as FDA approval. FDA explains that when an ingredient qualifies as a new dietary ingredient, manufacturers or distributors may have notification obligations and must establish a reasonable expectation of safety under the proposed conditions of use.     8. What Are U.S. Buyers Looking for in Cycloastragenol? For CQHERB, this is perhaps the most important commercial section. Based on the current U.S. supplier landscape, buyers can be divided into several groups. 1. Nutraceutical Ingredient Companies These companies may be looking for: · bulk Cycloastragenol · standardized Astragalus extract · high-purity material · stable supply · documentation · private-label ingredient support 2. Dietary Supplement Manufacturers Potential applications include formulations positioned around: · healthy aging · longevity research · cellular health · telomere research 3. Research Institutions Researchers may require: · ≥98% purity · analytical characterization · COA · HPLC data · MS data · NMR data · SDS · batch traceability 4. Ingredient Distributors Distributors typically prioritize: · competitive pricing · MOQ flexibility · reliable lead time · export documentation · repeatable specifications · private-label or OEM support     9. Why High-Purity Cycloastragenol Matters For a specialized botanical active, purity is only one part of quality. A professional supplier should be able to provide evidence for: Chemical Identity · Correct botanical source · Correct chemical identity · CAS/reference number · Molecular formula · Molecular weight Purity HPLC or another validated analytical method should be used to quantify the target compound. Commercial U.S. suppliers currently list Cycloastragenol products at ≥98% HPLC, establishing this as a recognizable research-grade specification. Batch-to-Batch Consistency For commercial formulation, consistent purity between batches is critical. Contaminant Control Depending on the intended market, buyers may request: · Heavy metals · Residual solvents · Microbial testing · Pesticide residues · Mycotoxins · Other botanical contaminants Documentation A professional B2B package may include: · COA · Specification Sheet · SDS · HPLC chromatogram · MS data · NMR data · Certificate of Origin · Manufacturing information     10. Cycloastragenol CAS Number: An Important Buyer Check This deserves a separate section because it can cause confusion during international sourcing. Different scientific databases and commercial suppliers currently display different CAS associations for Cycloastragenol. For example: · FDA's Substance Registration System identifies Cycloastragenol with UNII X37D9F2L0V and lists 78574-94-4 among its synonyms/mappings. · Sigma-Aldrich lists a Cycloastragenol product under CAS 78574-94-4. · NLM's MeSH database associates Cycloastragenol with 84605-18-5. · Sigma-Aldrich also has a separate product record under 84605-18-5. Therefore, professional buyers should verify CAS, stereochemical identity, InChIKey, analytical data and supplier documentation together, rather than relying on the CAS number alone. For CQHERB's final product page, I recommend using the exact identity appearing on your own: COA + Specification + HPLC + MS/NMR documentation. This will make the product page much more credible to U.S. technical buyers.     11. Cycloastragenol vs Astragaloside IV These two ingredients are often confused because they are both associated with Astragalus. Feature Cycloastragenol Astragaloside IV Category Triterpenoid sapogenin Triterpenoid saponin Botanical association Astragalus Astragalus Molecular Formula C₃₀H₅₀O₅ Different molecular structure Research focus Telomerase, cellular aging, signaling Saponin/pharmacological research Typical positioning High-purity active / longevity research Astragalus saponin research Commercial form Powder / high-purity compound Powder / standardized extract Buyer priority Purity & chemical identity Purity & standardized content Cycloastragenol is particularly attractive when a customer wants a defined active molecule rather than a broad-spectrum Astragalus extract.     12. Potential Applications for Cycloastragenol CQHERB can position Cycloastragenol for several B2B applications. Nutraceutical Research · Healthy-aging formulations · Longevity-oriented products · Cellular health formulations · Botanical active research Research & Development · Telomerase research · Telomere biology · Cellular aging · Oxidative stress · NRF2-related research · Immune-cell research Cosmetic Research Potential research interest may include: · skin aging · cellular protection · skin barrier research · oxidative stress · fibroblast/keratinocyte models These should be described as research and formulation applications, not as established disease-treatment claims.     13. How to Choose a Cycloastragenol Supplier When sourcing Cycloastragenol internationally, buyers should ask at least the following questions: 1. What is the exact chemical identity? Ask for: · CAS · Molecular formula · Molecular weight · Structure · InChIKey if available 2. What is the actual purity? Do not rely only on: “98% Cycloastragenol” Ask: 98% by which analytical method? 3. Can the supplier provide HPLC data? A chromatogram provides substantially more information than a simple specification statement. 4. Is the product botanical-derived or synthetic? This distinction can be commercially important depending on the application. 5. What is the source plant? For botanical material, buyers should confirm: Astragalus membranaceus and the relevant plant part, such as root. 6. Can the supplier provide batch documentation? A professional B2B supplier should be able to provide relevant documentation upon request.     14. Why Work With CQHERB for Cycloastragenol? At CQHERB, our positioning is not simply: “We sell Cycloastragenol.” Our goal is to provide research-oriented botanical ingredients with transparent specifications and professional technical support. For Cycloastragenol buyers, CQHERB can support projects requiring: High-Purity Cycloastragenol Suitable for research, ingredient development and specialized formulation projects. Astragalus-Based Botanical Ingredients For customers who need broader Astragalus extracts rather than isolated Cycloastragenol. Technical Documentation Available documentation can include: · COA · Specification Sheet · SDS · Analytical information · Botanical source information · Batch information Flexible B2B Supply We can support different purchasing requirements, from: Laboratory Samples → Small R&D Orders → Pilot Projects → Commercial Bulk Supply International B2B Support CQHERB is positioned to support overseas buyers with: · Product selection · Technical documentation · Sample evaluation · Packaging · Export support · Bulk quotation     15. CQHERB Technical Insight Why Cycloastragenol Is Different From a Conventional Astragalus Extract A conventional botanical extract contains a complex mixture of compounds. Cycloastragenol provides a more specific chemical target. This distinction can be important for: Research reproducibility and formulation standardization. For research applications, a defined compound allows researchers to better control: · concentration · dose · experimental conditions · analytical measurement · batch comparison For commercial formulations, a defined active may also make it easier to establish a consistent ingredient specification. This is one reason high-purity Cycloastragenol can occupy a different commercial position from a conventional Astragalus root extract.     16. U.S. Market Positioning Strategy for Cycloastragenol For the U.S. market, we recommend positioning Cycloastragenol around four major themes: 01 — Healthy Aging The strongest consumer-facing category. 02 — Telomerase Research The strongest scientific keyword. 03 — Premium Botanical Active The strongest ingredient-industry positioning. 04 — High-Purity B2B Supply The strongest commercial positioning for CQHERB. This creates a clear product story: Astragalus → Cycloastragenol → Telomerase Research → Healthy Aging → Premium Botanical Ingredient → B2B Supply     17. Regulatory Considerations for the U.S. Market This point should be handled carefully on a professional B2B website. FDA distinguishes dietary supplements from drugs. Dietary supplements fall under the food regulatory framework, while products intended to diagnose, cure, mitigate, treat or prevent disease may fall into drug territory. For ingredients that qualify as new dietary ingredients, FDA's NDI framework may require premarket notification and information supporting a reasonable expectation of safety under the proposed conditions of use. Therefore, CQHERB should avoid statements such as: ❌ “Cycloastragenol treats aging.” ❌ “Cycloastragenol cures age-related diseases.” ❌ “Clinically proven to extend human lifespan.” Instead, use: ✅ “Cycloastragenol has been investigated for telomerase activity.” ✅ “Cycloastragenol is a research-active compound associated with Astragalus.” ✅ “Research has explored its potential relevance to cellular aging pathways.” This approach makes the website more suitable for both scientific audiences and international B2B buyers.     18. Frequently Asked Questions What is Cycloastragenol? Cycloastragenol is a naturally occurring triterpenoid sapogenin associated with Astragalus species, particularly Astragalus membranaceus. Is Cycloastragenol the same as Astragalus extract? No. Astragalus extract is a complex botanical preparation, while Cycloastragenol is a specific triterpenoid constituent associated with Astragalus. What is Cycloastragenol used for? Cycloastragenol is studied in areas including telomerase activity, cellular aging, oxidative stress and immune-cell biology. Is Cycloastragenol popular in the U.S.? There is clear commercial and research activity in the U.S. market. Major scientific suppliers and U.S. nutraceutical companies currently offer Cycloastragenol products. What purity should I buy? For research and specialized ingredient applications, ≥98% HPLC is a commonly encountered high-purity specification among commercial research suppliers. Can Cycloastragenol be used in dietary supplements? The regulatory status depends on the exact ingredient, formulation, intended use, labeling and applicable U.S. requirements. Buyers should conduct a product-specific regulatory review rather than assuming that commercial availability equals FDA approval. FDA's NDI framework is relevant where an ingredient qualifies as a new dietary ingredient. Does Cycloastragenol extend human lifespan? Current scientific literature does not establish that Cycloastragenol extends human lifespan. Research has primarily focused on biological mechanisms such as telomerase activity and cellular pathways. What documents should I request from a supplier? At minimum: · COA · Specification Sheet · HPLC · SDS · Botanical source · Batch information · Heavy-metal testing where applicable · Residual-solvent testing where applicable     19. Why Choose CQHERB Cycloastragenol? If you are sourcing Cycloastragenol for nutraceutical development, botanical research, healthy-aging formulations or commercial ingredient applications, CQHERB can provide a professional B2B supply solution. Our focus is: High Purity Consistent Quality Transparent Documentation Reliable Supply Technical Support Global B2B Service Whether you need a laboratory sample, a development batch or commercial-volume supply, our team can work with you to determine the appropriate Cycloastragenol specification for your project.     20. Conclusion Cycloastragenol represents an important specialized ingredient at the intersection of Astragalus botanical science, telomerase research, healthy aging and the growing longevity-oriented ingredient market. The U.S. market already provides several signals of commercial interest: Cycloastragenol is listed by established scientific suppliers, appears in U.S. nutraceutical products and has a history of regulatory interaction through an NDI notification involving a Cycloastragenol-rich Astragalus extract. For B2B buyers, however, the opportunity is closely connected to quality and documentation. A reliable Cycloastragenol supplier should provide more than a purity number. Buyers should evaluate chemical identity, analytical methodology, botanical source, batch consistency and supporting documentation. CQHERB aims to provide Cycloastragenol and Astragalus-derived botanical ingredients for international research, nutraceutical and ingredient-development markets, with a focus on quality, transparency and reliable B2B supply.  

Dimethylcurcumin (ASC-J9) CAS 52328-98-0: Chemical Properties, Androgen Receptor Research, Applications & Buying Guide A Research-Oriented Guide to a Curcumin Analogue and Androgen Receptor Degradation Enhancer CAS No. 52328-98-0 | Molecular Formula C23H24O6 | Molecular Weight 396.43 g/mol     Quick Answer Dimethylcurcumin, commonly known as ASC-J9 or GO-Y025, is a synthetic curcumin analogue that has been extensively investigated in laboratory and preclinical research related to androgen receptor (AR) signaling. Its chemical identity is associated with CAS No. 52328-98-0, molecular formula C23H24O6, and molecular weight 396.43 g/mol. Unlike conventional androgen receptor antagonists that primarily interfere with androgen binding or receptor signaling, ASC-J9 has been investigated as an androgen receptor degradation enhancer. Research has examined its ability to promote degradation of androgen receptor proteins and thereby alter AR-dependent signaling in experimental models. Published studies have investigated ASC-J9 in a range of experimental systems, including prostate cancer models, androgen receptor-associated disorders, bladder cancer models, and spinal and bulbar muscular atrophy research. These studies include in vitro cellular experiments and in vivo animal models; such findings should not be interpreted as evidence of established clinical efficacy in humans. For researchers and organizations sourcing Dimethylcurcumin, important purchasing considerations include chemical identity, purity, analytical characterization, batch consistency, storage conditions, and supporting technical documentation.     Key Takeaways · Dimethylcurcumin is also known as ASC-J9 and GO-Y025. · CAS Number: 52328-98-0. · Molecular Formula: C23H24O6. · Molecular Weight: 396.43 g/mol. · It is a synthetic curcumin analogue, rather than native curcumin itself. · ASC-J9 has been investigated as an androgen receptor degradation enhancer. · Published research has examined its effects on AR protein degradation and AR-related signaling. · Research has included prostate cancer, bladder cancer, spinal and bulbar muscular atrophy, and other AR-associated experimental models. · Research-grade ASC-J9 is commonly supplied as a solid/powder and may require low-temperature storage depending on the supplier's specification. · Analytical verification is important when purchasing high-purity Dimethylcurcumin for research. · ASC-J9 should be presented on a research-oriented website as a research compound, not as an approved therapeutic product.     1. What Is Dimethylcurcumin (ASC-J9)? Dimethylcurcumin is a synthetic compound structurally related to curcumin and is widely known in the scientific literature as ASC-J9. The compound is identified chemically as: (1E,4Z,6E)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one Public chemical databases list Dimethylcurcumin, ASC-J9, and GO-Y025 among its synonyms. PubChem identifies CAS No. 52328-98-0 and molecular formula C23H24O6, with a molecular weight of approximately 396.4 g/mol. Commercial research suppliers also identify ASC-J9 using the same CAS number and molecular formula and commonly describe high-purity material as a research-grade powder. Although its name contains "curcumin," Dimethylcurcumin should not be treated as simply another commercial grade of curcumin. It is a distinct synthetic curcumin analogue with its own molecular structure and research profile. This distinction is particularly important for purchasing, analytical testing, literature searches, and regulatory documentation.     2. Dimethylcurcumin vs. Curcumin The relationship between Dimethylcurcumin and curcumin is an important point for researchers. Curcumin is a naturally occurring diarylheptanoid associated with Curcuma longa. Dimethylcurcumin, by contrast, is a chemically modified analogue that contains methoxy-substituted aromatic groups and has a different molecular formula and molecular weight. Property Dimethylcurcumin / ASC-J9 Curcumin Common Name Dimethylcurcumin Curcumin CAS 52328-98-0 458-37-7 Formula C23H24O6 C21H20O6 Molecular Weight 396.43 g/mol 368.38 g/mol Relationship Synthetic curcumin analogue Naturally occurring curcuminoid Research Focus AR degradation and AR-related signaling Broad pharmacological and biochemical research Research Status Experimental/research compound Widely studied natural compound The two compounds therefore should not be substituted for one another simply because they belong to the broader curcumin-analogue research area.     3. Chemical Identification of ASC-J9 Accurate chemical identification is particularly important for research compounds because different suppliers may use overlapping synonyms. Core Chemical Information Property Information Product Name Dimethylcurcumin Common Research Name ASC-J9 Alternative Name GO-Y025 CAS Number 52328-98-0 Molecular Formula C23H24O6 Molecular Weight 396.43 g/mol Chemical Class Curcumin analogue IUPAC Name (1E,4Z,6E)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one Physical Form Solid / powder Research Target Androgen receptor-related research The identity and molecular information above are supported by PubChem and commercial analytical product records.     4. Why Is ASC-J9 Important in Research? The scientific interest surrounding ASC-J9 largely comes from its unusual relationship with the androgen receptor. The androgen receptor (AR) is a nuclear receptor that regulates gene transcription in response to androgen hormones. AR signaling has important physiological roles and has also been extensively investigated in diseases and biological conditions in which androgen signaling is altered. ASC-J9 attracted research attention because studies indicated that it could promote AR protein degradation, rather than simply competing with androgens for receptor binding. This creates an important conceptual distinction: ASC-J9 research focuses on changing the abundance and activity of AR protein, while conventional antiandrogen research often focuses on blocking receptor activation. Early research demonstrated that ASC-J9 could disrupt interactions between AR and selected coregulators and increase AR degradation in experimental systems. Subsequent studies expanded this research into additional AR-associated models.     5. How Does ASC-J9 Work in Experimental Research? AR Degradation as a Research Mechanism One of the defining characteristics of ASC-J9 is its reported ability to enhance degradation of androgen receptor protein. Research has suggested that ASC-J9 can interfere with interactions between AR and selected coregulators, leading to increased AR degradation. Experimental work has also linked ASC-J9-mediated AR degradation to proteasome-dependent processes. This mechanism is different from simply reducing androgen production. The conceptual pathway can be simplified as: ASC-J9 ↓ Alteration of AR–coregulator interactions ↓ Enhanced AR degradation ↓ Reduced AR protein abundance ↓ Changes in AR-dependent transcription ↓ Changes in downstream cellular responses This model has been investigated primarily through laboratory and animal studies.     6. What Does the Scientific Literature Show? Research on ASC-J9 spans more than a decade. An early study published in Nature Medicine investigated ASC-J9 in a model of spinal and bulbar muscular atrophy. The study reported that ASC-J9 disrupted interactions between androgen receptor and coregulators and increased degradation of the mutant androgen receptor in experimental systems. The researchers also investigated the compound in transgenic mice. Later research examined ASC-J9 in prostate cancer models. Studies reported degradation of both full-length AR and an AR splice variant in experimental prostate cancer cell models, accompanied by reduced AR transcriptional activity and cell growth. Additional preclinical studies investigated ASC-J9 in combination with other experimental approaches, including radiation and chemotherapy models. For example, research published in Cancer Letters examined the combination of ASC-J9 with docetaxel in castration-resistant prostate cancer models. A review published in 2021 summarized research involving ASC-J9 across multiple AR-associated disease models, including prostate cancer, benign prostatic hyperplasia, bladder cancer, liver disease, spinal and bulbar muscular atrophy, ovarian cancer, and melanoma. Important Scientific Qualification These publications demonstrate research interest and preclinical findings, not established clinical efficacy. Therefore, CQHERB's website should describe ASC-J9 in terms such as: · Research compound · Research chemical · Curcumin analogue · AR degradation research · Experimental compound · Preclinical research and should avoid presenting ASC-J9 as an approved medicine or making direct therapeutic claims.     7. Research Applications of Dimethylcurcumin ASC-J9 has been investigated in several research areas. 7.1 Androgen Receptor Research This is the most characteristic research application. Researchers use ASC-J9 to investigate: · AR protein degradation · AR signaling · AR transcriptional activity · AR–coregulator interactions · AR-dependent cellular pathways     7.2 Prostate Cancer Research ASC-J9 has been investigated in multiple prostate cancer cell and animal models, including models of castration-resistant prostate cancer. Studies have examined whether AR degradation can alter tumor-cell proliferation and AR-dependent signaling. These findings remain within the context of experimental research and should not be presented as evidence that ASC-J9 is an approved cancer treatment.     7.3 Spinal and Bulbar Muscular Atrophy Research ASC-J9 has also been studied in models of spinal and bulbar muscular atrophy, a condition associated with mutant androgen receptor aggregation. The original study reported that ASC-J9 reduced mutant AR aggregation and improved disease-related phenotypes in experimental mice.     7.4 Bladder Cancer Research Research has also investigated ASC-J9 in bladder cancer models, particularly in relation to AR and NF-κB signaling and chemotherapy response.     8. Analytical Considerations for ASC-J9 For research-grade Dimethylcurcumin, chemical identity and purity should be verified through appropriate analytical methods. Commonly relevant analytical techniques include: HPLC HPLC can be used to evaluate chromatographic purity and batch consistency. LC-MS / MS Mass spectrometry can support molecular identity confirmation and quantitative analysis. A published analytical method specifically developed LC-MS/MS determination of ASC-J9 in mouse serum and tissues. NMR NMR can provide structural characterization and is particularly useful when confirming the identity of research compounds. COA A Certificate of Analysis should identify the product, batch, assay/purity, analytical method, and relevant quality parameters. For high-value research compounds, buyers should ideally review analytical documentation before placing larger orders.     CQHERB Technical Insight For Dimethylcurcumin and other research-oriented botanical or bioactive compounds, identity and analytical traceability should be considered alongside purity. A reliable research-material supplier should be able to clearly distinguish: Product identity → analytical method → purity → batch information → storage → documentation This is especially important for ASC-J9 because the compound is known under several names, including Dimethylcurcumin, ASC-J9 and GO-Y025. Using the CAS number 52328-98-0 together with the molecular formula and analytical documentation can help minimize purchasing and identification errors.     9. Storage and Handling Publicly available research-product specifications commonly recommend storing ASC-J9 at low temperature, with −20°C being specified by several commercial research suppliers. For commercial research material, customers should follow the supplier-specific COA, SDS and storage instructions rather than relying on a generic recommendation. Recommended purchasing documentation should include: · Product specification · COA · SDS/MSDS · Storage conditions · Batch number · Retest or expiry information where applicable · Analytical data upon request     10. Who Uses Dimethylcurcumin? ASC-J9 is primarily relevant to organizations conducting laboratory and preclinical research. Potential users include: · University research laboratories · Pharmaceutical research organizations · Biotechnology companies · Molecular biology laboratories · Cancer biology research groups · Androgen receptor research laboratories · Drug discovery teams · Academic research institutions The appropriate use and regulatory status depend on the customer's jurisdiction, research protocol, and intended application.     11. Buyer Guide: How to Evaluate an ASC-J9 Supplier When sourcing Dimethylcurcumin, buyers should not evaluate suppliers based solely on the advertised purity number. A more complete evaluation should include: 1. Correct Chemical Identity Confirm: CAS 52328-98-0 and cross-check the molecular formula and analytical data. 2. Purity Method Ask whether the stated purity is determined by HPLC or another analytical method. 3. Batch Documentation Request a current COA corresponding to the actual batch. 4. Structural Confirmation For research-grade material, MS and/or NMR data can provide additional confidence in chemical identity. 5. Storage Confirm storage temperature and packaging conditions. 6. Supply Consistency For repeated research programs, batch-to-batch consistency can be more important than obtaining the lowest initial quotation.     12. Why Research Buyers Should Distinguish ASC-J9 From Curcumin One common purchasing error is assuming that Dimethylcurcumin can be substituted with curcumin simply because ASC-J9 is a curcumin analogue. This is incorrect. The two compounds have different molecular formulas, molecular weights, structures, and research profiles. Therefore, research protocols specifying: ASC-J9 / Dimethylcurcumin / CAS 52328-98-0 should not automatically be replaced with curcumin or another curcuminoid. For reproducible experimental research, the exact compound specified in the protocol should be sourced and analytically verified.     13. Frequently Asked Questions What is ASC-J9? ASC-J9 is a research name for Dimethylcurcumin, a synthetic curcumin analogue investigated particularly for its ability to enhance androgen receptor degradation. What is the CAS number of ASC-J9? The CAS number is 52328-98-0. What is the molecular formula of Dimethylcurcumin? The molecular formula is C23H24O6. What is the molecular weight of ASC-J9? The molecular weight is approximately 396.43 g/mol. Is ASC-J9 the same as curcumin? No. ASC-J9 is a distinct synthetic curcumin analogue with a different molecular structure and molecular formula. What is ASC-J9 mainly researched for? ASC-J9 has been extensively investigated in androgen receptor-related research, particularly research involving AR degradation and signaling. Is ASC-J9 a conventional androgen receptor antagonist? Its research mechanism is distinct from conventional AR antagonists. ASC-J9 has primarily been investigated as an AR degradation enhancer, affecting AR protein abundance rather than simply blocking androgen binding. What research models have been used? Published research includes cell-based studies and animal models involving prostate cancer, spinal and bulbar muscular atrophy, bladder cancer, and other AR-associated conditions. How should ASC-J9 be stored? Several commercial research specifications recommend storage at approximately −20°C, but buyers should follow the storage instructions supplied with the specific batch. What documents should I request when purchasing ASC-J9? At minimum, buyers should consider requesting a COA and SDS/MSDS. For research applications, HPLC, MS and/or NMR information may also be useful.     14. References & Further Reading For the published scientific basis of this guide, useful starting points include: 1. Yang Z, et al. ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor. Nature Medicine. 2. Lai KP, et al. Research on ASC-J9 and androgen receptor degradation in prostate cancer models. 3. Cheng MA, et al. Androgen receptor degradation enhancer ASC-J9® in an FDA-approved formulated solution suppresses castration resistant prostate cancer cell growth. Cancer Letters. 4. Hu H, Zhou H, Xu D. A review of the effects and molecular mechanisms of dimethylcurcumin (ASC-J9) on androgen receptor-related diseases. Chemical Biology & Drug Design. 2021. 5. Research on LC-MS/MS determination and pharmacokinetic distribution of ASC-J9 in experimental animals. 6. Research investigating ASC-J9 in combination with chemotherapy in experimental prostate cancer models.     Looking for Dimethylcurcumin (ASC-J9) for Research? CQHERB provides botanical extracts and research-oriented bioactive compounds for international customers, with technical documentation available according to product and batch. For Dimethylcurcumin (ASC-J9), CAS 52328-98-0, customers can discuss requirements such as: · Required purity · Research quantity · COA · HPLC analytical data · MS/NMR documentation where available · SDS/MSDS · Packaging · Storage requirements · International shipment requirements For research and formulation development, please contact the CQHERB technical sales team with your required quantity and specification.

Methyl Maslinate CAS 22425-82-7 | Maslinic Acid Methyl Ester Methyl Maslinate, also known as Maslinic Acid Methyl Ester or Crategolic Acid Methyl Ester, is a defined pentacyclic triterpenoid derivative identified by CAS No. 22425-82-7. It has the molecular formula C31H50O4 and a molecular weight of approximately 486.73 g/mol. For B2B buyers, Methyl Maslinate is best understood as a defined research compound associated with natural-product chemistry, rather than as a conventional multi-component botanical extract. CQ HERB supplies Methyl Maslinate for research, analytical and development applications with batch-specific documentation according to the agreed specification.     Quick Answer What is Methyl Maslinate? Methyl Maslinate is the methyl ester form of maslinic acid and is also known as Maslinic Acid Methyl Ester and Crategolic Acid Methyl Ester. The compound is identified by: CAS: 22425-82-7 Molecular Formula: C31H50O4 Molecular Weight: 486.73 g/mol Chemical Class: Pentacyclic triterpenoid derivative PubChem lists Methyl Maslinate under CID 3082208 and records its molecular structure, formula, synonyms and natural-product occurrence data.     Key Takeaways Product Name: Methyl Maslinate Chinese Name: 马斯里酸甲酯 Alternative Name: Maslinic Acid Methyl Ester Other Name: Crategolic Acid Methyl Ester CAS No.: 22425-82-7 Molecular Formula: C31H50O4 Molecular Weight: 486.73 g/mol Chemical Class: Pentacyclic triterpenoid derivative Form: Powder Typical Research Specification: ≥99% HPLC*, subject to batch specification Positioning: Research and analytical compound Documentation: COA, HPLC, SDS and TDS PubChem's current record confirms the chemical identity and reports natural-product occurrence data for Methyl Maslinate.     1. Chemical Identity Methyl Maslinate is a defined triterpenoid derivative rather than a generic plant extract. Basic Information Property Information Product Name Methyl Maslinate CAS Number 22425-82-7 Molecular Formula C31H50O4 Molecular Weight 486.73 g/mol Alternative Name Maslinic Acid Methyl Ester Other Name Crategolic Acid Methyl Ester Chemical Class Pentacyclic triterpenoid derivative Product Form Powder The molecular formula and molecular weight are supported by PubChem and other chemical reference sources.     2. Methyl Maslinate and Maslinic Acid Methyl Maslinate and maslinic acid are structurally related compounds, but they should not be treated as identical materials. Property Maslinic Acid Methyl Maslinate Chemical Type Pentacyclic triterpenoid Triterpenoid ester derivative CAS 4373-41-5 22425-82-7 Molecular Formula C30H48O4 C31H50O4 Molecular Weight Approx. 472.70 g/mol Approx. 486.73 g/mol Key Structural Feature Carboxylic acid Methyl ester Research Positioning Natural-product research Triterpenoid derivative research For procurement, researchers should always confirm the exact CAS number rather than relying on the generic term "maslinic acid."     3. Natural-Product Background Methyl Maslinate is associated with natural-product chemistry and has been reported in several plant-related datasets. PubChem's LOTUS-linked information records Methyl Maslinate or maslinic acid methyl ester in organisms including Isodon japonicus, Cunila lythrifolia and Prunella vulgaris. This information is useful for natural-product researchers, but natural occurrence should not automatically be interpreted as the manufacturing source of a commercial batch. Therefore, suppliers should clearly distinguish between: Natural occurrence and Manufacturing source For CQ HERB, the actual source and manufacturing route should be stated according to the specific product and production process.     4. Structural Information Methyl Maslinate belongs to the pentacyclic triterpenoid family. Its molecular formula is: C31H50O4 and its molecular weight is: 486.73 g/mol PubChem provides detailed structural information, including the compound's InChI, InChIKey, SMILES and systematic chemical name. This information can be useful when researchers compare Methyl Maslinate with related triterpenoids.     5. Why CAS 22425-82-7 Matters The term "maslinate" can be confusing because multiple related triterpenoid compounds may appear in natural-product literature. For procurement, buyers should confirm: CAS No.: 22425-82-7 and cross-check: Molecular formula Molecular weight Chemical structure HPLC purity COA Batch information This provides a more reliable basis for material identification.     6. Research Applications Methyl Maslinate can be positioned for several research contexts without making therapeutic or health claims. Natural-Product Chemistry Methyl Maslinate can be used as a defined triterpenoid-related compound in natural-product chemistry research. Analytical Research A characterized Methyl Maslinate material can be used where an analytical compound or reference material is required. Structural Research Its defined molecular structure allows researchers to compare it with related pentacyclic triterpenoids and ester derivatives. Biochemical Research Methyl Maslinate has appeared in scientific research involving biochemical and molecular systems. For commercial communication, these should be described as research contexts, rather than as evidence of a health benefit.     7. Methyl Maslinate as a Research Compound A key distinction between Methyl Maslinate and a conventional botanical extract is chemical definition. A botanical extract may contain multiple compounds, while an isolated Methyl Maslinate product is intended to provide a specific chemical entity with a defined molecular identity. This makes parameters such as: CAS number Purity HPLC profile Molecular formula Molecular weight Batch number particularly relevant to researchers.     8. HPLC and Quality Control For research-grade Methyl Maslinate, analytical characterization is an important part of supplier evaluation. CQ HERB can provide quality documentation according to the agreed specification, including: COA HPLC purity HPLC chromatogram SDS TDS Product specification Batch information Storage recommendations For customers requiring a specific analytical method, the testing requirements should be confirmed before production or shipment.     9. Appearance and Physical Form Methyl Maslinate is generally supplied as a powder or solid material. Public chemical databases and commercial references describe the compound as a solid material, while specific color descriptions may vary between suppliers. For CQ HERB's official product specification, the appearance and color should always correspond to the actual production batch. Recommended wording: Appearance: Powder If a specific color is confirmed by your current COA, that color can be added to the specification.     10. Storage and Handling Methyl Maslinate should be stored in a tightly sealed container under controlled conditions. General storage recommendations include: Keep dry. Protect from moisture. Protect from excessive light. Minimize prolonged exposure to air. Follow the storage conditions stated on the product SDS and COA. For long-term storage, the actual validated storage recommendation for the supplied batch should be followed.     11. How to Select a Methyl Maslinate Supplier 1. Confirm CAS Number 22425-82-7 2. Confirm Molecular Formula C31H50O4 3. Confirm Molecular Weight 486.73 g/mol 4. Check HPLC Purity Ask for the actual batch HPLC result rather than relying solely on a website specification. 5. Request COA A professional COA should identify the material and corresponding batch. 6. Request Supporting Documentation Depending on the application, buyers may require: COA HPLC chromatogram SDS TDS Product specification Batch information Export documentation     12. Methyl Maslinate vs. Other Triterpenoids Methyl Maslinate belongs to a broad group of pentacyclic triterpenoid-related compounds. For research procurement, compounds should not be selected solely by a general category such as "triterpenoid." Researchers should confirm the exact chemical identity. Parameter Methyl Maslinate CAS 22425-82-7 Formula C31H50O4 MW 486.73 g/mol Chemical Class Pentacyclic triterpenoid derivative Form Powder Research Position Defined research compound     13. Why Choose CQ HERB? CQ HERB supplies Methyl Maslinate for professional B2B research and development applications. Our supply support can include: Research-grade material Batch-specific COA HPLC testing SDS TDS Flexible packaging Small research quantities Bulk supply Export documentation Customized analytical requirements For customers evaluating Methyl Maslinate for a new project, we recommend confirming purity, quantity, packaging and documentation requirements before quotation.     Frequently Asked Questions What is Methyl Maslinate? Methyl Maslinate is a pentacyclic triterpenoid derivative also known as Maslinic Acid Methyl Ester or Crategolic Acid Methyl Ester. What is the CAS number of Methyl Maslinate? The CAS number is 22425-82-7. What is the molecular formula? The molecular formula is C31H50O4. What is the molecular weight? The molecular weight is approximately 486.73 g/mol. Is Methyl Maslinate the same as maslinic acid? No. Methyl Maslinate is a methyl ester derivative of maslinic acid and has a different molecular formula and molecular weight. Is Methyl Maslinate a plant extract? No. Methyl Maslinate is a defined chemical compound associated with natural-product chemistry. It should not be described simply as a conventional botanical extract. What is Methyl Maslinate used for? It is supplied primarily for research, analytical and natural-product chemistry applications. Can CQ HERB provide an Methyl Maslinate sample? Sample quantities can be discussed according to research requirements and current availability. What documentation is available? Typical documentation includes COA, HPLC data, SDS and TDS according to the applicable product specification.     Technical Data Summary Item Information Product Methyl Maslinate Alternative Name Maslinic Acid Methyl Ester Other Name Crategolic Acid Methyl Ester CAS 22425-82-7 Formula C31H50O4 Molecular Weight 486.73 g/mol Chemical Class Pentacyclic triterpenoid derivative Form Powder Purity ≥99% HPLC* Application Research & analytical use Documentation COA / HPLC / SDS / TDS * Subject to actual batch specification.     Research Use Disclaimer For Research Use Only. This product is supplied as a research and analytical material. It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, or use as a pharmaceutical or dietary supplement unless separately authorized under applicable regulations.

Dimethylcurcumin (ASC-J9): Chemical Identity, Research Applications and Buyer Guide Dimethylcurcumin, also known as ASC-J9 or GO-Y025, is a defined chemical compound associated with curcumin-related chemical research. With CAS No. 52328-98-0, molecular formula C23H24O6, and molecular weight 396.43 g/mol, it is supplied as a research material for laboratory, analytical, biochemical, and chemical research. For researchers and B2B buyers evaluating Dimethylcurcumin, understanding its chemical identity, analytical specifications, documentation, and supply form is more important than relying on biological activity claims. CQ HERB supplies research-grade Dimethylcurcumin with batch-specific quality documentation according to the agreed specification.     Quick Answer What is Dimethylcurcumin (ASC-J9)? Dimethylcurcumin is a synthetic curcumin-related compound identified by CAS 52328-98-0. It is also known as: · ASC-J9 · ASC J9 · GO-Y025 · Dimethylcurcumin According to PubChem, Dimethylcurcumin has the molecular formula C23H24O6 and a molecular weight of approximately 396.43 g/mol. PubChem also records ASC-J9 and GO-Y025 among its synonyms. Unlike conventional curcumin obtained from botanical sources, Dimethylcurcumin should be described as a defined synthetic chemical compound, rather than as a conventional Curcuma longa extract.     Key Takeaways · Product Name: Dimethylcurcumin · Research Code: ASC-J9 · Alternative Name: GO-Y025 · CAS No.: 52328-98-0 · Molecular Formula: C23H24O6 · Molecular Weight: 396.43 g/mol · Appearance: Powder · Chemical Category: Curcumin-related synthetic compound · Typical Research Grade: ≥98% HPLC, subject to batch specification · Primary Positioning: Research and analytical material · Documentation: COA, HPLC data, SDS and TDS according to specification Commercial research suppliers also list ASC-J9 under CAS 52328-98-0 with ≥98% HPLC specifications.     1. Chemical Identity of Dimethylcurcumin Chemical identity is one of the most important factors when sourcing research compounds. Basic Information Property Information Product Name Dimethylcurcumin CAS Number 52328-98-0 Molecular Formula C23H24O6 Molecular Weight 396.43 g/mol Synonyms ASC-J9; GO-Y025 Chemical Type Synthetic curcumin-related compound Appearance Powder Research Use Laboratory and analytical research The molecular identity, CAS number, formula and molecular weight are supported by PubChem and other chemical reference databases.     2. Dimethylcurcumin vs. Curcumin Although the names are related, Dimethylcurcumin and conventional curcumin are different chemical compounds. Property Dimethylcurcumin Curcumin Common Name Dimethylcurcumin Curcumin CAS 52328-98-0 458-37-7 Molecular Formula C23H24O6 C21H20O6 Molecular Weight 396.43 g/mol 368.38 g/mol Chemical Position Synthetic curcumin-related compound Natural curcuminoid Typical Source Description Defined chemical compound Botanical-associated compound Research Positioning Research compound Natural-product / biochemical research This distinction is particularly important when purchasing material for analytical or laboratory work. A supplier should not describe Dimethylcurcumin simply as "curcumin" because the two compounds have different chemical identities.     3. Why CAS 52328-98-0 Matters A product name can sometimes be used inconsistently between suppliers. For procurement and laboratory work, the most reliable starting point is the CAS number: CAS No.: 52328-98-0 Buyers should cross-check the CAS number against: · Molecular formula · Molecular weight · Structural information · HPLC specification · COA · Batch information This helps reduce the risk of receiving a related but chemically different curcuminoid or research compound.     4. Structural Information Dimethylcurcumin is a defined organic molecule with the molecular formula C23H24O6. Its systematic chemical name is: (1E,4Z,6E)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one PubChem records the structure, InChI, InChIKey, SMILES and related chemical identifiers for CAS 52328-98-0. For research projects involving structure-based analysis, these identifiers can be more useful than a commercial product name alone.     5. Research Context ASC-J9 has appeared in scientific and biochemical research involving molecular signaling and androgen receptor-related mechanisms. However, the presence of published research does not mean that a commercial Dimethylcurcumin product should be described as a therapeutic product. For responsible B2B communication, CQ HERB recommends describing ASC-J9 using neutral terminology such as: "Dimethylcurcumin is a research compound investigated in laboratory studies involving molecular signaling pathways." This wording identifies the scientific context without presenting experimental findings as a product benefit.     6. Research Applications Dimethylcurcumin may be relevant to several laboratory research contexts. Chemical Research Researchers can use Dimethylcurcumin as a defined chemical material for studies involving curcumin-related molecular structures and derivatives. Analytical Research A characterized Dimethylcurcumin material can be used where a defined analytical compound or reference material is required. Biochemical Research ASC-J9 has been investigated in laboratory research involving molecular and biochemical pathways. Comparative Research Dimethylcurcumin can also be included in comparative studies involving structurally related compounds. These descriptions refer to research contexts only and do not constitute therapeutic or medical claims.     7. HPLC and Quality Control For research compounds, identity and purity are critical procurement considerations. CQ HERB recommends evaluating Dimethylcurcumin using appropriate analytical methods, including HPLC where applicable. Typical documentation may include: · Certificate of Analysis (COA) · HPLC purity result · HPLC chromatogram · Product specification · SDS · TDS · Batch information · Storage recommendation For example, commercial research suppliers list ASC-J9 with ≥98% HPLC specifications. CQ HERB specifications should always be based on the actual production batch and current COA.     8. Appearance and Physical Form Dimethylcurcumin is generally supplied as a powder or solid material. Public chemical references report powder/solid physical forms, with color descriptions varying by source. For commercial specifications, the actual CQ HERB batch specification should take priority over generic database descriptions. A product specification may therefore state: Appearance: Powder with the specific color described according to the applicable batch COA.     9. Solubility and Laboratory Preparation Dimethylcurcumin has limited water solubility and may be prepared using suitable organic laboratory solvents depending on the experimental system. Published commercial reference information lists DMSO among solvents used for laboratory preparation. Researchers should select solvents and concentrations according to their own validated experimental protocols.     10. Storage and Handling Dimethylcurcumin should be stored according to the supplier's current product specification and SDS. Recommended general practices include: · Keep the container tightly closed. · Protect from moisture. · Protect from excessive light. · Store under controlled temperature conditions. · Avoid unnecessary repeated exposure to air. Some commercial research references recommend low-temperature storage for ASC-J9. The storage condition stated on the supplied COA, label and SDS should take precedence.     11. How to Select a Dimethylcurcumin Supplier When comparing suppliers, buyers should consider more than the stated purity. Check the CAS Number Confirm: 52328-98-0 Check the Molecular Formula Confirm: C23H24O6 Check the Molecular Weight Confirm: 396.43 g/mol Request HPLC Data Ask for the actual batch HPLC result and, when appropriate, the chromatogram. Request a COA The COA should identify the: · Product · CAS number · Batch number · Test result · Test method · Specification Check Documentation For international procurement, buyers may also need: · SDS · TDS · COA · HPLC chromatogram · Commercial invoice · Packing list · Export documentation     12. Why Choose CQ HERB? CQ HERB supplies Dimethylcurcumin for B2B research and development applications. Our support can include: · Research-grade material · Batch-specific COA · HPLC testing · SDS · TDS · Flexible packaging · Small research quantities · Bulk supply · Export documentation · Customized analytical requirements For projects requiring a specific purity or analytical method, buyers are encouraged to confirm the specification before placing an order.     Frequently Asked Questions What is ASC-J9? ASC-J9 is a research code name associated with Dimethylcurcumin, CAS 52328-98-0. Is ASC-J9 the same as curcumin? No. Dimethylcurcumin and curcumin are different chemical compounds with different molecular formulas and molecular weights. What is the CAS number of Dimethylcurcumin? The CAS number is 52328-98-0. What is the molecular formula? The molecular formula is C23H24O6. What is the molecular weight? The molecular weight is approximately 396.43 g/mol. Is Dimethylcurcumin a plant extract? No. CAS 52328-98-0 should be treated as a defined chemical compound rather than a conventional botanical extract. What is Dimethylcurcumin used for? It is supplied primarily as a research and analytical material for laboratory and chemical research. Can CQ HERB provide a COA? Yes. A batch-specific COA can be provided according to the applicable product specification. Is a sample available? Sample quantities can be discussed according to research requirements and current availability.     Technical Data Summary Item Information Product Dimethylcurcumin Research Code ASC-J9 Alternative Name GO-Y025 CAS 52328-98-0 Formula C23H24O6 Molecular Weight 396.43 g/mol Form Powder Purity ≥98% HPLC* Application Research & analytical use Documentation COA / HPLC / SDS / TDS * Subject to actual batch specification.     Research Use Disclaimer For Research Use Only. This product is supplied as a research and analytical material. It is not intended for human or veterinary use, diagnosis, treatment, cure, prevention of disease, or use as a pharmaceutical or dietary supplement unless separately authorized under applicable regulations.

    Oridonin (98%) Ultimate Guide A Technical Guide to Structure, Natural Sources, Research, Production, Quality Control and Supplier Selection Oridonin is a naturally occurring diterpenoid isolated primarily from Isodon rubescens, a plant traditionally known in China as Dong Ling Cao. It has attracted substantial scientific interest because of its distinctive ent-kaurane-type molecular framework, diverse natural-product chemistry, and extensive research across molecular biology, pharmacology, pharmaceutical chemistry, and drug-discovery research. For manufacturers and research organizations, however, understanding Oridonin requires more than reviewing its reported biological activities. The quality of a commercial Oridonin material depends on its botanical source, extraction and purification process, analytical methodology, purity specification, batch consistency, and supporting technical documentation. This guide provides a research-oriented overview of Oridonin, with particular attention to high-purity 98% Oridonin, including its chemical identity, natural source, physicochemical characteristics, production considerations, analytical quality control, research applications, and practical supplier evaluation.     Quick Answer What Is Oridonin? Oridonin is a naturally occurring ent-kaurane-type diterpenoid primarily associated with Isodon rubescens, a member of the Lamiaceae family. Its CAS number is 28957-04-2, molecular formula is C20H28O6, and molecular weight is approximately 364.4 g/mol. Oridonin is one of the most extensively studied diterpenoids found in Isodon rubescens. Modern research has investigated its molecular interactions, cellular pathways, pharmacokinetic characteristics, structural modifications, and potential applications in natural-product and pharmaceutical research. From a commercial perspective, high-purity Oridonin is different from a conventional Isodon rubescens or Dong Ling Cao extract. A standardized botanical extract contains multiple naturally occurring constituents, whereas 98% Oridonin is a purified single compound with a defined molecular identity and a much narrower analytical specification. This distinction makes high-purity Oridonin particularly relevant to laboratories and manufacturers that require reproducible research materials, defined chemical composition, and quantitative analytical control. For buyers, evaluating Oridonin quality should therefore go beyond the stated purity. Important considerations include HPLC methodology, chromatographic profile, identity confirmation, residual solvents, heavy metals, moisture, storage conditions, batch consistency, and the supplier's ability to provide complete technical documentation.     Key Takeaways Oridonin is a naturally occurring diterpenoid primarily associated with Isodon rubescens. CAS 28957-04-2 is the commonly recognized CAS identifier for Oridonin. Its molecular formula is C20H28O6, with a molecular weight of approximately 364.4 g/mol. Kew's Plants of the World Online currently accepts Isodon rubescens as the species name, while Rabdosia rubescens is treated as a synonym. Oridonin belongs to the ent-kaurane diterpenoid family. Isodon rubescens contains numerous diterpenoids and other secondary metabolites, with Oridonin among its best-studied constituents. High-purity Oridonin and Isodon rubescens extract are not interchangeable products. HPLC is an important analytical tool for evaluating Oridonin purity and the quality of Isodon rubescens-derived materials. Research on Oridonin includes natural-product chemistry, molecular mechanisms, pharmacokinetics, structural modification, and drug-discovery studies. Its relatively limited aqueous solubility and bioavailability remain important considerations in pharmaceutical research. For B2B procurement, purity should be evaluated together with identity, analytical methodology, documentation, and batch consistency.     Table of Contents What Is Oridonin? Why Is Oridonin Scientifically Important? Oridonin Chemical Structure and Properties Natural Source: Isodon rubescens Oridonin vs. Isodon rubescens Extract How Is High-Purity Oridonin Produced? Oridonin Quality Standards and HPLC Analysis Oridonin Solubility and Stability Considerations Research Applications of Oridonin Oridonin Derivatives and Structural Modification How to Choose a Reliable Oridonin Supplier Buyer Checklist for Oridonin 98% Frequently Asked Questions CQHERB Technical Insight Scientific References     1. What Is Oridonin? Oridonin is a naturally occurring diterpenoid found primarily in Isodon rubescens. It belongs to a structurally diverse family of plant-derived diterpenes and is characterized as an ent-kaurane-type diterpenoid. The compound has been extensively investigated because of its distinctive polycyclic molecular framework and multiple oxygen-containing functional groups. These structural characteristics make Oridonin an important subject in natural-product chemistry and medicinal chemistry research. The accepted botanical name is currently Isodon rubescens (Hemsl.) H.Hara, according to the Royal Botanic Gardens, Kew. Rabdosia rubescens is treated by Kew as a synonym. Both names therefore appear frequently in scientific publications and commercial literature. Definition Oridonin is a naturally occurring ent-kaurane diterpenoid with the molecular formula C20H28O6 and CAS 28957-04-2, primarily isolated from Isodon rubescens.     2. Why Is Oridonin Scientifically Important? Oridonin has attracted sustained scientific attention for several reasons. First, it represents a structurally distinctive natural-product scaffold. Second, it can be isolated and purified as a chemically defined compound, allowing researchers to investigate its molecular properties independently of the many other constituents found in the plant. Third, a substantial body of research has investigated Oridonin in cellular, biochemical, pharmacokinetic, and medicinal-chemistry contexts. Reviews published in recent years have summarized research involving signaling pathways, cell-cycle regulation, apoptosis, autophagy, oxidative processes, and other molecular phenomena. Importantly, much of this literature concerns preclinical or experimental research. Findings from cell models or animal studies should not automatically be interpreted as evidence of established clinical efficacy in humans. This distinction is particularly important when presenting Oridonin on a commercial website.     Why Does High-Purity Oridonin Matter? Research reproducibility is strongly influenced by material consistency. A crude botanical extract can contain numerous compounds whose concentrations vary according to: Plant origin Cultivar or genetic background Growing conditions Harvesting period Extraction method Processing conditions Storage A purified Oridonin material reduces many of these variables by providing a defined target compound. For laboratory and formulation-development work, high-purity Oridonin can therefore offer: Defined chemical identity Standardized purity Better batch-to-batch consistency More reproducible analytical results Easier comparison between experiments More precise formulation calculations     Scientific Research Timeline Research Stage General Development Early natural-product research Isolation and structural characterization of Oridonin Later phytochemical research Expansion of research on Isodon diterpenoids Modern analytical research Improved HPLC and LC-MS characterization Molecular research era Increasing investigation of cellular and signaling mechanisms Recent research Structural modification, delivery systems, pharmacokinetics, and drug-discovery studies The continuing development of analytical and biochemical technologies has allowed researchers to investigate Oridonin at increasingly detailed molecular levels. Section Summary Oridonin is scientifically important not simply because it originates from a traditional medicinal plant, but because it combines a distinctive natural-product structure with extensive experimental research and the ability to be isolated as a defined compound.     3. Oridonin Chemical Structure and Physicochemical Properties Basic Chemical Information Property Information Common Name Oridonin CAS Number 28957-04-2 Molecular Formula C20H28O6 Molecular Weight 364.4 g/mol Chemical Class ent-Kaurane diterpenoid Natural Source Isodon rubescens Typical High-Purity Specification ≥98% by HPLC The molecular identity and basic chemical information are consistent with the PubChem record for Oridonin.     What Makes the Oridonin Structure Interesting? Oridonin possesses a complex tetracyclic diterpenoid framework containing several oxygenated functional groups and an enone-related structural motif. This combination of structural features contributes to the compound's importance in medicinal-chemistry research. Researchers have also used the Oridonin scaffold as a starting point for chemical modification. Various derivatives have been investigated with the goal of modifying properties such as solubility, stability, pharmacokinetics, and biological activity.     Key Definitions DiterpenoidA natural product generally derived from four isoprene units and containing 20 carbon atoms. ent-Kaurane diterpenoidA structural class of diterpenoids characterized by a specific tetracyclic carbon skeleton. HPLCHigh-Performance Liquid Chromatography, an analytical technique commonly used to separate, identify, and quantify components in a sample. PurityThe proportion of the target compound relative to other detectable components under a defined analytical method.     Section Summary Oridonin's defined molecular formula and distinctive ent-kaurane diterpenoid structure make it suitable for detailed analytical and medicinal-chemistry research. Its structural framework has also become a useful starting point for investigating chemically modified derivatives.     4. Natural Source: Isodon rubescens What Plant Produces Oridonin? The principal natural source associated with Oridonin is Isodon rubescens (Hemsl.) H.Hara, a species in the Lamiaceae family. Kew currently recognizes Isodon rubescens as the accepted name and lists Rabdosia rubescens as a synonym. The species is native to central and southern China. The plant is commonly known in Chinese contexts as Dong Ling Cao (冬凌草), and the dried aerial parts have a long history of use in traditional Chinese medicine.     Phytochemical Complexity of Isodon rubescens One important point for buyers is that Isodon rubescens is not an Oridonin-only plant. Scientific reviews have documented a large number of secondary metabolites from the species, including: Diterpenoids Triterpenoids Phenolic compounds Alkaloids Volatile constituents Other specialized metabolites Among these constituents, diterpenoids represent one of the most extensively studied groups, with Oridonin being one of the best-known compounds.     Why Botanical Source Matters The concentration of individual compounds in a botanical raw material can vary according to: Plant genetics Geographic origin Cultivation conditions Harvest time Plant part Drying conditions Extraction technology Research on Rabdosia rubescens has also demonstrated that the contents of several compounds can vary among different cultivars, reinforcing the importance of analytical quality control. Section Summary Isodon rubescens is the principal botanical source associated with Oridonin. Because the plant contains a complex mixture of diterpenoids and other secondary metabolites, high-purity Oridonin requires dedicated extraction and purification rather than simple botanical extraction.     5. Oridonin vs. Isodon rubescens Extract This distinction is particularly important for international buyers. Feature Oridonin 98% Isodon rubescens Extract Product Type Purified single compound Multi-component botanical extract Main Target Oridonin Multiple plant constituents Purity Specification Typically expressed as Oridonin % by HPLC May use extract ratio or marker-compound specification Chemical Composition Narrowly defined Complex Research Reproducibility High when analytical method is controlled Dependent on extract specification Typical Use Research, analytical and formulation development Botanical ingredient research and formulation Quality Control HPLC, identity, impurities and other specifications Marker compounds, extraction ratio, contaminants and other specifications Buyer Tip If a project requires a defined concentration of Oridonin, purchasing a standardized high-purity Oridonin material is generally more straightforward than relying on a conventional Isodon rubescens extract. If the project specifically requires the broader phytochemical profile of the plant, a standardized botanical extract may be more appropriate. Section Summary Oridonin 98% and Isodon rubescens extract should not be treated as equivalent products. The former is a purified compound; the latter is a complex botanical preparation with multiple constituents.     6. How Is High-Purity Oridonin Produced? From Botanical Raw Material to Purified Compound The production of high-purity Oridonin requires several stages because the target compound occurs together with numerous other constituents in the plant. A simplified production concept is: Botanical Raw Material ↓ Extraction ↓ Filtration / Concentration ↓ Fractionation ↓ Purification ↓ Crystallization or Further Refinement ↓ Drying ↓ HPLC Testing ↓ High-Purity Oridonin The exact process depends on the manufacturer's technology, raw material specification, target purity, scale, and analytical requirements.     Extraction The first objective is to transfer Oridonin and related constituents from the plant matrix into an appropriate extract. Extraction parameters may influence: Yield Impurity profile Solvent consumption Downstream purification requirements     Purification Crude extracts contain many naturally occurring compounds. Therefore, achieving a high Oridonin specification requires selective separation from: Other diterpenoids Pigments Phenolic constituents Lipophilic components Other plant-derived impurities Published research has demonstrated the use of chromatographic technologies such as high-speed counter-current chromatography for the isolation and purification of Oridonin from Isodon rubescens.     HPLC Verification Following purification, analytical testing is used to determine whether the material meets the required specification. HPLC can provide information about: Retention time   Target peak Relative purity Chromatographic profile Potential impurities Research has also developed HPLC-based methods for simultaneous characterization and quantification of multiple compounds in Rabdosia rubescens, highlighting the importance of chromatographic analysis in quality control.     CQHERB Technical Insight For high-purity botanical monomers, the manufacturing challenge is not simply "extracting more compound." The key challenge is achieving selective purification while maintaining reproducible analytical quality. This is why a professional supplier should be able to explain not only the final purity but also the analytical method used to verify that specification.     7. Oridonin Quality Standards and HPLC Analysis Is 98% Purity Enough? Not necessarily. A 98% purity statement is useful, but it should be interpreted together with the analytical method and supporting documentation. When evaluating an Oridonin 98% material, buyers should review: 1. HPLC Purity Confirm how the 98% value was determined. Questions may include: Which HPLC method was used? Is the method clearly described? Is the chromatogram available? Is the purity calculated by area normalization or another method? 2. Identity The supplier should be able to demonstrate that the tested compound is Oridonin rather than another diterpenoid with a similar chromatographic behavior. 3. Chromatographic Profile A chromatogram can provide useful information about: Main peak Retention time Secondary peaks Overall sample profile 4. Residual Solvents If organic solvents are used during manufacturing, residual solvent testing may be appropriate depending on the intended application and applicable standards. 5. Heavy Metals and Contaminants For botanical-derived materials, buyers may also request information concerning: Lead Cadmium Arsenic Mercury Microbiological parameters     Recommended Technical Documents For international B2B procurement, a professional supplier should be prepared to provide, where applicable: Certificate of Analysis (COA) Product Specification HPLC Chromatogram SDS / MSDS Technical Data Sheet Residual Solvent Information Heavy Metal Information Packaging Information Storage Recommendations     8. Oridonin Solubility and Stability Considerations Solubility is an important technical issue when working with Oridonin. Published research has identified relatively limited aqueous solubility and bioavailability as important challenges in the development of Oridonin-based pharmaceutical formulations. Researchers have investigated approaches including structural modification, formulation technologies, nanoparticles, liposomes, and co-crystals to address these limitations. For research and formulation developers, this means that Oridonin should not be evaluated only according to chemical purity. Practical considerations can include: Solvent selection Concentration Temperature Storage conditions Light exposure Container compatibility Formulation matrix     Why Solubility Matters in Research Two samples with identical HPLC purity can behave differently in a practical formulation if: Particle size differs Sample preparation differs Solvent systems differ Storage history differs Experimental temperature differs Therefore, research protocols should clearly document sample preparation conditions when Oridonin is used in solution-based experiments. Section Summary Oridonin's physicochemical characteristics, particularly its limited aqueous solubility, are important considerations for research and formulation development. High chemical purity does not automatically guarantee easy formulation or high bioavailability.     9. Research Applications of Oridonin Oridonin has been investigated across several areas of scientific research. Natural Product Chemistry Researchers study Oridonin as a representative ent-kaurane diterpenoid and as one component of the complex phytochemistry of Isodon rubescens. Research topics include: Isolation Structural elucidation Derivatization Analytical characterization Natural-product biosynthesis     Molecular and Cellular Research A large body of experimental literature has examined Oridonin in relation to cellular processes such as: Apoptosis Autophagy Cell-cycle regulation Oxidative stress Inflammatory signaling Cellular metabolism These findings are predominantly based on laboratory and preclinical models and should not be interpreted as proof of clinical efficacy. Recent reviews continue to examine Oridonin's proposed molecular mechanisms and its interaction with multiple signaling pathways.     Pharmaceutical Chemistry Research Oridonin has also become a useful starting scaffold for medicinal-chemistry research. Researchers have explored structural modifications designed to address challenges such as: Poor aqueous solubility Limited bioavailability Rapid clearance Pharmacokinetic limitations Oridonin derivatives have therefore become a separate research area within natural-product drug discovery.     Analytical Research Because Oridonin is a defined chemical compound, it can also be used in: HPLC method development LC-MS analysis Reference-material research Botanical quality-control studies Comparative phytochemical analysis   Important Research Disclaimer The biological activities described in scientific literature do not mean that Oridonin 98% sold as a research ingredient is an approved pharmaceutical or that it is intended to diagnose, treat, cure, or prevent disease. Research findings should always be interpreted according to the experimental model, concentration, formulation, and study design.     10. Oridonin Derivatives and Structural Modification One particularly interesting aspect of Oridonin research is the development of chemically modified derivatives. The natural Oridonin scaffold has been used as a starting point for exploring changes to functional groups and molecular regions that may affect: Solubility Stability Target interaction Pharmacokinetics Biological activity Reviews of Oridonin derivatives have documented extensive medicinal-chemistry research aimed at improving properties of the parent compound. This research demonstrates an important principle in natural-product chemistry: A natural compound can serve not only as a research material itself, but also as a structural template for the development of new chemical entities. Section Summary Oridonin continues to attract interest as both a natural compound and a chemical scaffold. Research on its derivatives illustrates the intersection between botanical chemistry, medicinal chemistry, and modern drug-discovery research.     11. How to Choose a Reliable Oridonin Supplier For B2B buyers, selecting an Oridonin supplier should involve more than comparing prices. 1. Confirm Product Identity Check: CAS number Chemical name Molecular formula Molecular weight HPLC profile 2. Confirm Purity Method Ask how the 98% specification is determined and request the corresponding analytical documentation. 3. Review Batch Documentation A current-batch COA is more useful than a generic specification sheet. 4. Evaluate Manufacturing Capability Understand whether the supplier: Manufactures the material Controls purification Performs analytical testing Maintains batch records 5. Evaluate Technical Support For research-grade ingredients, technical communication can be as important as price. A reliable supplier should be able to answer questions about Purity HPLC Solubility Storage Packaging Lead time Documentation     12. Buyer Checklist for Oridonin 98% Before placing an order, buyers can use the following checklist. Confirm CAS 28957-04-2 Confirm molecular formula C20H28O6 Confirm molecular weight Confirm ≥98% HPLC specification Request current-batch COA Request HPLC chromatogram Confirm identity-testing method Review residual solvent information Review heavy-metal information Confirm packaging Confirm storage conditions Confirm sample availability Confirm production lead time Confirm technical documentation Evaluate long-term supply capability     13. Frequently Asked Questions What is Oridonin? Oridonin is a naturally occurring ent-kaurane diterpenoid primarily associated with Isodon rubescens. Its CAS number is 28957-04-2. What is the CAS number of Oridonin? The commonly recognized CAS number is 28957-04-2. What is the molecular formula of Oridonin? The molecular formula is C20H28O6. What is the molecular weight of Oridonin? The molecular weight is approximately 364.4 g/mol. What plant does Oridonin come from? Oridonin is primarily associated with Isodon rubescens, a species in the Lamiaceae family. Rabdosia rubescens is a recognized synonym. Is Oridonin the same as Dong Ling Cao extract? No. Dong Ling Cao or Isodon rubescens extract is a complex botanical preparation, while Oridonin is a purified individual compound. What does 98% Oridonin mean? It generally indicates that Oridonin constitutes at least approximately 98% of the material according to the stated analytical method, commonly HPLC. The analytical method should always be reviewed alongside the stated purity. How is Oridonin purity tested? HPLC is commonly used for quantitative analysis and purity assessment. Additional techniques such as LC-MS or NMR can be used for identity characterization depending on the application. Is Oridonin water soluble? Oridonin has limited aqueous solubility, which has been identified as an important technical challenge in pharmaceutical formulation research. What is Oridonin used for? High-purity Oridonin is primarily relevant to scientific research, natural-product chemistry, analytical studies, pharmaceutical chemistry, and formulation-development research. Is Oridonin an approved drug? Research into Oridonin and Oridonin derivatives is ongoing, but a research-grade Oridonin ingredient should not be represented as an approved pharmaceutical merely because pharmacological studies have been published. What is the difference between Oridonin and other Isodon diterpenoids? Isodon rubescens contains numerous diterpenoids. Oridonin is one specific compound with its own chemical identity, molecular formula, and analytical profile. Can Oridonin be used as an analytical reference material? High-purity Oridonin can be relevant to analytical research, but suitability as a formal reference standard depends on the required certification, purity characterization, intended analytical method, and applicable standards. Why is HPLC important for Oridonin? HPLC provides a practical way to separate and quantify Oridonin and assess the chromatographic profile of a sample. What documents should an Oridonin supplier provide? Typical documents may include COA, specification sheet, HPLC chromatogram, SDS/MSDS, and technical data. Additional documents depend on the customer's application and regulatory requirements. How should Oridonin be stored? Storage recommendations should follow the supplier's validated specification and stability information. In general, minimizing unnecessary exposure to heat, moisture, and light is a prudent approach for purified natural products. Can Oridonin derivatives be synthesized? Yes. Numerous research programs have investigated structural modification of Oridonin to explore changes in physicochemical and biological properties. Why do researchers study Oridonin derivatives? One major reason is to investigate whether structural modification can address limitations of the parent compound, including solubility and pharmacokinetic characteristics. What should buyers check before purchasing Oridonin 98%? The most important items include identity, HPLC purity, chromatogram, COA, production source, analytical method, contaminants, storage conditions, and supplier consistency. Is Oridonin 98% the same as a 98% Isodon rubescens extract? No. "98% Oridonin" describes a purified compound specification, whereas "98% Isodon rubescens extract" would describe a very different product concept and should not be assumed to have the same chemical composition.     14. CQHERB Technical Insight Purity Is Only One Part of Botanical Monomer Quality For high-purity botanical compounds such as Oridonin, it is tempting to evaluate suppliers based solely on the number printed on the COA. However, professional procurement requires a broader view. A robust quality assessment should consider: Identity Is the material actually Oridonin? Purity Does the material meet the stated ≥98% specification? Analytical Method How was the purity determined? Chromatographic Profile Does the HPLC chromatogram demonstrate a clean and consistent profile? Contaminant Control Are residual solvents, heavy metals, moisture, and microbiological parameters appropriately controlled? Batch Consistency Can the supplier provide the same specification repeatedly? Traceability Can the material be traced to a defined manufacturing and testing process? This approach is particularly important when Oridonin is used in research projects where reproducibility is more important than simply achieving the lowest purchase price.     15. Industry Insight The development of Oridonin reflects a broader trend in the botanical ingredient industry: the transition from complex traditional extracts toward well-characterized natural compounds. Researchers and manufacturers increasingly require: Defined molecular identity Standardized purity Reliable analytical data Consistent batch quality Transparent technical documentation At the same time, advances in natural-product chemistry are creating new opportunities for studying botanical compounds as molecular scaffolds rather than simply as traditional herbal extracts. Oridonin is a particularly useful example of this transition because research has expanded from simple isolation and characterization to molecular mechanisms, pharmacokinetics, structural modification, delivery technologies, and derivative development.     Why We Published This Guide The purpose of this guide is not to promote Oridonin through unsupported efficacy claims. Instead, CQHERB aims to provide researchers, manufacturers, and purchasing professionals with a practical technical reference for understanding: What Oridonin is Where it comes from How it differs from botanical extracts How high-purity material is evaluated Why HPLC matters What technical challenges researchers should consider How to evaluate suppliers For botanical ingredients, reliable information is an essential part of product quality.     Final Summary Oridonin is a structurally distinctive ent-kaurane diterpenoid primarily associated with Isodon rubescens. With a molecular formula of C20H28O6 and CAS 28957-04-2, it has become one of the most extensively studied diterpenoids from this botanical source. Modern research extends from natural-product isolation and structural characterization to molecular biology, pharmacokinetics, formulation science, and the development of Oridonin derivatives. At the same time, researchers continue to investigate challenges such as limited aqueous solubility and bioavailability. For B2B buyers, the key consideration is that 98% Oridonin is a purified single compound rather than a conventional Isodon rubescens extract. Its quality should therefore be evaluated through a combination of purity, identity, HPLC profile, contaminant control, documentation, and batch consistency. As scientific interest in standardized natural compounds continues to expand, Oridonin represents an important example of how traditional botanical resources can become well-characterized materials for modern natural-product and pharmaceutical research.     Looking for a Reliable Oridonin Supplier? If you are sourcing high-purity Oridonin (98%) for research, analytical development, formulation studies, or long-term B2B supply, technical specifications should be evaluated according to your intended application. CQHERB can provide product information and technical documentation for evaluation, including: COA Product Specification HPLC Chromatogram SDS/MSDS Technical Data Sample Support Packaging Information Request Technical Information     Scientific References PubChem. Oridonin – CID 5321010. National Center for Biotechnology Information. Royal Botanic Gardens, Kew. Plants of the World Online: Isodon rubescens (Hemsl.) H.Hara. Royal Botanic Gardens, Kew. Rabdosia rubescens (Hemsl.) H.Hara – synonym of Isodon rubescens. Ali MA, et al. Oridonin from Rabdosia rubescens: An emerging potential in cancer therapy – A comprehensive review. Food Science & Nutrition. 2024. Zhang Y, Wang S, Dai M, et al. Solubility and Bioavailability Enhancement of Oridonin: A Review. Molecules. 2020;25(2):332. Oridonin: A Review of Its Pharmacology, Pharmacokinetics and Toxicity. PubMed-indexed review. Sobral PJM, Vicente ATS, Salvador JAR. Recent advances in oridonin derivatives with anticancer activity. Frontiers in Chemistry. 2023. The Natural Product Oridonin as an Anticancer Agent: Current Achievements and Problems. PubMed-indexed review. 2023. Isolation and Purification of Oridonin from the Whole Plant of Isodon rubescens by High-Speed Counter-Current Chromatography. Simultaneous characterization and quantification of 17 main compounds in Rabdosia rubescens by high performance liquid chromatography. PubMed. Recent Advances on the Molecular Mechanisms of Apoptosis Induced by Natural Product Oridonin and Its Derivatives. 2026 review. Anticancer mechanisms on pyroptosis induced by Oridonin: New potential targeted therapeutic strategies. Biomedicine & Pharmacotherapy. 2023.   The bioavailability enhancement and insight into the action mechanism of poorly soluble natural compounds from co-crystals preparation: Oridonin as an example. Phytomedicine. 2024. Discovery and development of natural product oridonin-inspired anticancer agents. PubMed-indexed review. Research progress and molecular mechanism of oridonin in the treatment of malignant melanoma. 2025 review.     Content Classification Content Type: Ultimate Guide / Pillar PageKnowledge Base Category: Botanical Extract Knowledge BasePrimary Search Intent: Informational + Commercial InvestigationTarget Audience: Researchers, formulators, manufacturers, procurement professionals and ingredient buyersRecommended Content Cluster: Oridonin Ultimate Guide↓What Is Oridonin?↓Oridonin Chemical Structure↓Oridonin Solubility & Stability↓Oridonin HPLC & COA Guide↓Oridonin Extraction & Purification↓Oridonin vs. Isodon rubescens Extract↓How to Choose an Oridonin Supplier↓Oridonin FAQ Hub     Important Editorial Note This article intentionally distinguishes scientific research findings from established clinical or commercial claims. Oridonin has been extensively investigated in experimental systems, but published preclinical findings should not be presented as proof of human therapeutic efficacy. This positioning helps maintain the professional, research-oriented character of the CQHERB Knowledge Base and reduces unnecessary regulatory and advertising risk.

Cyclopamine is a naturally occurring steroidal alkaloid associated with the plant *Veratrum californicum*, commonly known as corn lily or California false hellebore. It has attracted considerable attention in biochemical and cell-signaling research because of its interaction with the Hedgehog (Hh) signaling pathway.   For researchers and technical buyers, cyclopamine is primarily relevant as a research compound and molecular tool for investigating Hedgehog signaling, Smoothened (SMO), and related cellular processes.   This guide provides an overview of cyclopamine's chemical identity, botanical origin, research background, mechanism of action in the Hedgehog pathway, analytical considerations, and procurement considerations for laboratory research.   Research-use notice: Cyclopamine is discussed here as a research compound. The information on this page is provided for scientific and educational purposes and is not intended to describe cyclopamine as a pharmaceutical product or to recommend its use for the diagnosis, prevention, or treatment of any disease.   Quick Answer   Cyclopamine is a naturally occurring steroidal alkaloid associated with *Veratrum californicum*. Its CAS number is **4449-51-8**, and its molecular formula is **C27H41NO2**, with a molecular weight of approximately 411.6 g/mol.   In biochemical research, cyclopamine is best known as a small-molecule modulator of the **Hedgehog signaling pathway**, particularly through interaction with **Smoothened (SMO)**.   Because of its historical botanical origin and well-established role in Hedgehog pathway research, cyclopamine is frequently used as a reference compound in studies involving cellular signaling, developmental biology, molecular pharmacology, and compound screening.   Cyclopamine Chemical Information The basic chemical information for cyclopamine is summarized below.   | Property                             | Information                                         | | ------------------------------------ | --------------------------------------------------- | | Product Name                         | Cyclopamine                                         | | CAS Number                           | 4449-51-8                                           | | Alternative Name                     | 11-Deoxojervine                                     | | Molecular Formula                    | C27H41NO2                                           | | Molecular Weight                     | 411.6 g/mol                                         | | Chemical Class                       | Steroidal alkaloid                                  | | Natural Source                       | *Veratrum* species                                  | | Commonly Associated Botanical Source | *Veratrum californicum*                             | | Research Area                        | Hedgehog signaling and related biochemical research | | Typical Research Form                | Solid / powder reference material                   |   According to PubChem, cyclopamine is also known by the synonym 11-deoxojervine and is classified as a steroidal alkaloid. PubChem records cyclopamine in several *Veratrum* species, including *Veratrum californicum*.   For procurement and analytical documentation, the CAS number **4449-51-8** is particularly important because it helps distinguish cyclopamine from other structurally related *Veratrum* alkaloids.   What Is the Botanical Source of Cyclopamine?   Cyclopamine is closely associated with *Veratrum californicum*, a plant commonly referred to as corn lily or California false hellebore.   *Veratrum californicum* is native to mountainous regions of western North America. The plant contains a group of structurally related steroidal alkaloids, including cyclopamine and other *Veratrum* alkaloids.   Research on *Veratrum californicum* has shown that the alkaloid composition can vary according to plant part, collection location, and growth stage. Modern analytical studies have identified cyclopamine together with other steroidal alkaloids in the plant.   This botanical variability is important when discussing plant extracts versus isolated compounds.   A **cyclopamine reference compound is not equivalent to a whole *Veratrum* extract**.   A botanical extract may contain multiple alkaloids and other plant constituents, while purified cyclopamine represents a defined chemical component. Research comparing *Veratrum californicum* extracts with individual alkaloids has demonstrated that different alkaloid combinations can produce different experimental effects in Hedgehog pathway assays.   Cyclopamine and the Hedgehog Signaling Pathway   One of the most important reasons cyclopamine is studied is its relationship with the Hedgehog signaling pathway.   The Hedgehog pathway is a conserved cellular signaling system involved in developmental and differentiation processes. In mammals, the pathway involves several key components, including:   * Hedgehog ligands * Patched (PTCH) receptors * Smoothened (SMO) * Suppressor of Fused (SUFU) * GLI transcription factors   When Hedgehog signaling is activated, changes in SMO activity influence downstream signaling events involving GLI transcription factors.   Cyclopamine became an important molecular research tool because it can interfere with Hedgehog pathway signaling at the level of Smoothened. Scientific literature describes cyclopamine as an antagonist of SMO and an inhibitor of Hedgehog pathway signaling.   This makes cyclopamine useful for laboratory studies designed to investigate the biological consequences of modulating Hedgehog signaling.   How Does Cyclopamine Interact With Smoothened?   Smoothened, commonly abbreviated as **SMO**, is a seven-transmembrane protein that plays a central role in Hedgehog signal transduction.   In simplified terms, Hedgehog signaling can be viewed as a regulatory sequence:   **Hedgehog ligand → PTCH → SMO → GLI → downstream gene expression**   Cyclopamine acts at the SMO stage of this signaling system.   Experimental studies have provided evidence that cyclopamine interacts with Smoothened and interferes with its signaling activity. This observation was important in establishing the relationship between cyclopamine and the Hedgehog pathway.   Because of this mechanism, cyclopamine is commonly included in experimental systems investigating:   * Hedgehog pathway activation * Smoothened signaling * GLI-dependent transcription * Cellular differentiation * Developmental signaling * Small-molecule pathway modulation * Mechanistic studies of Hedgehog-related biology   Importantly, these research applications should not be interpreted as an indication that cyclopamine is an approved therapeutic product.   Why Is Cyclopamine Important in Research?   Cyclopamine has a distinctive place in the history of Hedgehog signaling research.   Its botanical history preceded the discovery of its molecular mechanism. Research into abnormal developmental outcomes associated with ingestion of *Veratrum californicum* eventually led to the identification of cyclopamine as an active steroidal alkaloid. Decades later, studies established its connection with Hedgehog signaling.   This historical sequence made cyclopamine an important example of how a naturally occurring plant compound can contribute to the discovery and characterization of a cellular signaling pathway.   Today, cyclopamine continues to appear in scientific literature as a reference compound for studies involving Hedgehog pathway modulation.   A recent review of *Veratrum californicum* alkaloids also describes cyclopamine as the best-studied alkaloid from the plant in the context of Hedgehog signaling research.   Cyclopamine vs. *Veratrum californicum* Extract   One of the most common points of confusion is the difference between cyclopamine and *Veratrum californicum* extract.   | Feature            | Cyclopamine                                     | *Veratrum californicum* Extract                         | | ------------------ | ----------------------------------------------- | ------------------------------------------------------- | | Material Type      | Defined chemical compound                       | Botanical extract                                       | | Composition        | Primarily cyclopamine as the specified compound | Multiple naturally occurring constituents               | | CAS                | 4449-51-8                                       | Depends on extract specification                        | | Chemical Identity  | Defined                                         | Complex mixture                                         | | Research Use       | Molecular and biochemical research              | Botanical and phytochemical research                    | | Analytical Control | Can be specified by chemical purity             | Requires extract-specific marker or fingerprint testing | | Interchangeable?   | No                                              | No                                                      |   A whole-plant extract should therefore not be represented simply as “cyclopamine.”   The distinction is especially important for technical documentation, specifications, COAs, customs documents, and research applications.   Cyclopamine and Related *Veratrum* Alkaloids   *Veratrum* plants contain a range of steroidal alkaloids. Cyclopamine is only one member of this chemically diverse group.   Other compounds reported in *Veratrum californicum* research include:   * Veratramine * Muldamine * Isorubijervine * Jervine * Other structurally related steroidal alkaloids   Modern analytical studies have demonstrated substantial variation in alkaloid composition depending on plant material and extraction conditions.   For researchers working with purified cyclopamine, this distinction is useful because biological results obtained from a complex botanical extract cannot automatically be attributed to cyclopamine alone.   ## Analytical Identification of Cyclopamine   For research-grade cyclopamine, analytical characterization is an important part of quality control.   Common analytical approaches may include:   HPLC   High-performance liquid chromatography can be used to evaluate chromatographic purity and to monitor the presence of related components.   For a commercial research material, the analytical specification should clearly identify:   * Target compound * CAS number * Purity method * Analytical result * Batch number * Test date * Reference standard or analytical method where applicable   LC-MS   Liquid chromatography coupled with mass spectrometry can provide additional confirmation of molecular identity and help distinguish cyclopamine from structurally related *Veratrum* alkaloids.   Structural Information   PubChem lists cyclopamine under CAS 4449-51-8, molecular formula C27H41NO2, and molecular weight 411.6 g/mol.   For B2B research-material procurement, identity information should be consistent across the product specification, COA, SDS, label, and shipping documentation.   Factors to Consider When Purchasing Cyclopamine for Research   Researchers and purchasing teams should evaluate more than the stated purity percentage when sourcing cyclopamine.   1. Confirm the Chemical Identity   The CAS number should be clearly stated as:   **Cyclopamine — CAS 4449-51-8**   Alternative names such as 11-deoxojervine may also appear in scientific databases and literature.   2. Review the Analytical Specification   The supplier should be able to provide appropriate analytical documentation, such as:   * COA * HPLC chromatogram where available * Product specification * SDS * Batch information * Appearance * Purity result   3. Distinguish Purified Cyclopamine From Botanical Extract   If the project requires a defined compound, a whole *Veratrum* extract should not automatically be considered an equivalent material.   4. Consider Packaging   Cyclopamine should be handled and packaged according to the supplier's applicable chemical handling and storage specifications.   For international shipments, packaging should also be compatible with the requirements of the selected courier and destination country.   5. Check Documentation Before Shipment   International research-material shipments may require additional documentation depending on the destination, transport method, and local requirements.   Potential documentation can include:   * Commercial invoice * Packing list * SDS * COA * Product specification * Customs information * Transport-related documents where applicable   Buyers should confirm local import requirements before placing an international order.   Cyclopamine Storage and Handling   Cyclopamine is a research chemical and should be handled by appropriately trained personnel according to the supplier's SDS and laboratory procedures.   Storage conditions should follow the manufacturer's product specification and SDS rather than relying on generic recommendations.   For long-term storage, laboratories should also consider:   * Temperature control * Moisture exposure * Light exposure * Container integrity * Repeated opening and closing * Batch traceability   The appropriate storage conditions may depend on the specific product specification, formulation, packaging configuration, and intended research workflow.   Is Cyclopamine a Pharmaceutical Product?   Cyclopamine should not be presented as an approved pharmaceutical product on a commercial research-material website.   Its importance in the scientific literature is primarily related to its role as a research compound and Hedgehog pathway modulator.   Although scientific studies have investigated cyclopamine and related compounds in various biological models, research findings should not be converted into claims that a commercial cyclopamine product can diagnose, prevent, or treat a disease.   This distinction is particularly important for international websites and digital advertising.   Google Ads' current Healthcare and Medicines policy restricts promotion of certain unapproved substances and prohibits marketing that implies an unapproved product is safe or effective for preventing, curing, or treating a disease.   Research Areas Associated With Cyclopamine   Because of its interaction with Smoothened and Hedgehog signaling, cyclopamine appears in research involving several scientific fields.   Cell Signaling Research   Cyclopamine can be used as a chemical tool for investigating changes associated with Hedgehog pathway modulation.   Developmental Biology   The Hedgehog pathway has important roles in developmental biology, making cyclopamine relevant to experimental studies of pathway function.   Molecular Pharmacology   Cyclopamine has historically been used to investigate Smoothened and the molecular pharmacology of Hedgehog signaling.   Drug Discovery Research   Cyclopamine has also served as a reference structure in research exploring small-molecule Hedgehog pathway modulators and related chemical scaffolds.   These descriptions refer to research contexts and should not be interpreted as commercial therapeutic claims.   Cyclopamine and Modern Hedgehog Pathway Research   Cyclopamine was one of the earliest small molecules identified as capable of interfering with Hedgehog signaling.   Subsequent research led to the development and investigation of additional Smoothened-targeting compounds and other Hedgehog pathway modulators.   Scientific reviews describe cyclopamine as an important historical tool for understanding SMO and Hedgehog signaling, while also noting limitations that affected its development as a therapeutic candidate.   For current laboratory research, cyclopamine therefore has particular value as a **mechanistic research compound**, rather than as a commercial therapeutic ingredient.   Why Researchers Specify CAS 4449-51-8   CAS numbers are particularly useful when ordering specialized research compounds.   The name “cyclopamine” may appear together with alternative names such as:   * Cyclopamine * 11-Deoxojervine * 11-Deoxyjervine   Using the CAS number **4449-51-8** alongside the product name can reduce ambiguity during:   * Supplier communication * Purchase orders * COA review * SDS preparation * Customs documentation * Laboratory inventory management * Analytical database searches   PubChem currently identifies 4449-51-8 as the CAS number for cyclopamine and lists 11-deoxojervine among its synonyms.   CQ HERB Cyclopamine Research Material   CQ HERB provides botanical-derived research compounds and plant extract materials for B2B customers, with technical documentation available according to the specific product specification.   For cyclopamine-related inquiries, customers can discuss: * Required purity * Research quantity * Packaging * COA requirements * SDS requirements * Analytical documentation * Shipping destination * Documentation required for international shipment   For technical purchasing, we recommend confirming the exact specification before placing an order, particularly when the project requires a defined purity level or analytical method.   Frequently Asked Questions What is cyclopamine? Cyclopamine is a naturally occurring steroidal alkaloid associated with *Veratrum californicum*. It is widely discussed in scientific literature because of its interaction with the Hedgehog signaling pathway.   What is the CAS number of cyclopamine? The CAS number of cyclopamine is **4449-51-8**.   What is the molecular formula of cyclopamine?   The molecular formula is **C27H41NO2**, and PubChem lists a molecular weight of approximately **411.6 g/mol**.   What plant does cyclopamine come from? Cyclopamine is particularly associated with *Veratrum californicum*, commonly known as corn lily or California false hellebore. It has also been reported in other *Veratrum* species.   Is cyclopamine the same as *Veratrum californicum* extract? No. Cyclopamine is a defined chemical compound, whereas *Veratrum californicum* extract is a complex botanical mixture that may contain multiple steroidal alkaloids.   What is cyclopamine used for in research? Cyclopamine is primarily used as a research compound for studying Hedgehog signaling, Smoothened, and related cellular and molecular processes.   Is cyclopamine an approved medicine? Cyclopamine should not be represented on a commercial research-material website as an approved pharmaceutical product. Its primary relevance in this context is as a research compound.   Can cyclopamine be used in human or animal applications?   Any use involving humans or animals should be evaluated under the applicable institutional, regulatory, ethical, and safety requirements. This product page is intended for research and informational purposes and does not provide clinical or veterinary use recommendations.   How should cyclopamine be stored?   Storage should follow the specific supplier's SDS and product specification. Laboratories should maintain appropriate control of temperature, moisture, light exposure, and container integrity.   Key Takeaways * Cyclopamine is a naturally occurring steroidal alkaloid. * Its CAS number is **4449-51-8**. * Its molecular formula is **C27H41NO2**. * It is closely associated with *Veratrum californicum*. * Cyclopamine is widely recognized in scientific literature as a Hedgehog pathway research compound. * Its best-characterized molecular research target is Smoothened (SMO). * Purified cyclopamine should not be confused with whole-plant *Veratrum* extracts. * Research findings should not be presented as evidence of clinical efficacy or as a therapeutic recommendation. * Buyers should confirm identity, purity, analytical documentation, SDS, packaging, and shipping requirements before procurement.   References 1. PubChem. Cyclopamine, CID 442972. National Center for Biotechnology Information. 2. Pharmacology of *Veratrum californicum* Alkaloids as Hedgehog Pathway Antagonists. 3. Cyclopamine Bioactivity by Extraction Method from *Veratrum californicum*. 4. Hedgehog pathway as a drug target: Smoothened inhibitors in development. 5. Native *V. californicum* Alkaloid Combinations Induce Differential Inhibition of Sonic Hedgehog Signaling. 6. I only have eye for ewe: the discovery of cyclopamine and development of Hedgehog pathway-targeting drugs.   Disclaimer The information provided in this article is intended for scientific, educational, and research-reference purposes only. Cyclopamine is presented as a research compound and chemical reference material. Nothing on this page should be interpreted as medical advice, a therapeutic recommendation, or a claim that cyclopamine can diagnose, prevent, or treat any disease.   Users and purchasers are responsible for ensuring that their intended use, handling, storage, importation, and application of cyclopamine comply with applicable laws, regulations, institutional requirements, and safety procedures.